antibody

Goat anti-Vitamin D-binding protein/GC Antibody

MBS420897

0.1 mg

300 USD

polyclonal

goat

nonconjugated

western blot, enzyme immunoassay

Antibody

Goat anti-Vitamin D-binding protein/GC Antibody

Vitamin D-binding protein/GC

Goat Anti-VCBP / GC (aa 18 - 30) Antibody; GC; vitamin D-binding protein; group-specific component (vitamin D binding protein); DBP; DBP/GC; VDBG; VDBP; vitamin D binding protein; vitamin D-binding alpha-globulin; vitamin D-binding protein/group specific component; GC antibody; vitamin D-binding protein antibody; group-specific component (vitamin D binding protein) antibody; DBP antibody; DBP/GC antibody; VDBG antibody; VDBP antibody; vitamin D binding protein antibody; vitamin D-binding alpha-globulin antibody; vitamin D-binding protein/group specific component antibody; Vitamin D-binding protein; Vitamin D-binding protein / GC

vitamin D-binding protein isoform 1; Vitamin D-binding protein; vitamin D-binding protein; GC, vitamin D binding protein; Gc protein-derived macrophage activating factor

GC

GC; GC; DBP; GRD3; VDBG; VDBP; GcMAF; DBP/GC; Gc-MAF; HEL-S-51; DBP-maf

VTDB_HUMAN

Polyclonal

Goat

Tested: Human; Expected from sequence similarity: Human

474

CDNLSTKNSKFED

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Approx 56kDa band observed in Human Lung lysates (calculated MW of 52.9kDa according to NP_000574.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (DiMartino and Kew, J Immunol.1999 Aug 15;163(4): 2135-42; PMID: 10438954). Recommended concentration: 0.1-0.3ug/ml.

Immunogen: Peptide with sequence CDNLSTKNSKFED, from the internal region of the protein sequence according to NP_000574.2. Epitope: Internal region

32483410

NP_000574.2

NM_000583.3

55,123 Da

Metabolism Pathway (1269956); Metabolism Of Fat-soluble Vitamins Pathway (1339147); Metabolism Of Vitamins And Cofactors Pathway (1270144); Vitamin D (calciferol) Metabolism Pathway (1270052); Vitamin D Synthesis Pathway (198764)

The protein encoded by this gene belongs to the albumin gene family. It is a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid and on the surface of many cell types. It binds to vitamin D and its plasma metabolites and transports them to target tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

GC: Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 4q12-q13. Cellular Component: axon; cytosol; extracellular region; extracellular space; lysosomal lumen; perinuclear region of cytoplasm. Molecular Function: actin binding; vitamin D binding; vitamin transporter activity. Biological Process: female pregnancy; lactation; response to estradiol stimulus; response to nutrient levels; vitamin D metabolic process; vitamin transport. Disease: Graves Disease, Susceptibility To, 1

0.1 mg

300 USD