product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-THRB Antibody
catalog :
MBS420883
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS420883
products type :
Antibody
products full name :
Goat anti-THRB Antibody
products short name :
THRB
products name syn :
THRB; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); ERBA-BETA; ERBA2; GRTH; MGC126109; MGC126110; NR1A2; THR1; THRB1; THRB2; avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2; generalize; THRB antibody; thyroid hormone receptor; beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2; avian) antibody; ERBA-BETA antibody; ERBA2 antibody; GRTH antibody; MGC126109 antibody; MGC126110 antibody; NR1A2 antibody; THR1 antibody; THRB1 antibody; THRB2 antibody; avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2 antibody; generalized resistance to thyroid hormone antibody; oncogene ERBA2 antibody; thyroid hormone receptor beta 1 antibody; thyroid hormone receptor; beta antibody
other names :
thyroid hormone receptor beta; Thyroid hormone receptor beta; thyroid hormone receptor beta; thyroid hormone receptor beta; Nuclear receptor subfamily 1 group A member 2; c-erbA-2; c-erbA-beta
products gene name :
THRB
other gene names :
THRB; THRB; GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; C-ERBA-2; C-ERBA-BETA; ERBA2; NR1A2; THR1
uniprot entry name :
THB_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog
sequence length :
461
sequence :
REELQKSIGHKP
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 50+60kDa bands observed in Human Bone Marrow lysates (calculated MW of 52.8kDa according to NP_NP_000452.2 and of 54.5kDa according to EAW64350.1). Recommended concentration: 0.3-1ug/ml.
other info1 :
Immunogen: Peptide with sequence C-REELQKSIGHKP, from the internal region of the protein sequence according to NP_000452.2. Epitope: Internal region
other info2 :
Note: This antibody is not expected to cross-react to THRA.
ncbi gi num :
40806162
ncbi acc num :
NP_000452.2
ncbi gb acc num :
NM_000461.4
ncbi mol weight :
54,449 Da
ncbi pathways :
Gene Expression Pathway (1269649); Generic Transcription Pathway (1269650); Neuroactive Ligand-receptor Interaction Pathway (83053); Neuroactive Ligand-receptor Interaction Pathway (462); Nuclear Receptor Transcription Pathway (1269652); Nuclear Receptors Pathway (198848); SIDS Susceptibility Pathways (198901); Thyroid Hormone Signaling Pathway (946598)
ncbi summary :
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
size1 :
0.1 mg
price1 :
300 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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