catalog number :
MBS420870
products full name :
Goat anti-RGS1 / 1R20 Antibody
products short name :
RGS1/1R20
products name syn :
RGS1; 1R20; regulator of G-protein signalling 1; BL34; IER1; IR20; 1R20; Regulator of G-protein signaling 1; B-cell activation protein BL34; early response protein 1R20; immediate-early response 1; B-cell specific; RGS1; 1R20; regulator of G-protein signalling 1; BL34; IER1; IR20; 1R20; Regulator of G-protein signaling 1; B-cell activation protein BL34; early response protein 1R20; immediate-early response 1, B-cell specific
other names :
regulator of G-protein signaling 1; Regulator of G-protein signaling 1; regulator of G-protein signaling 1; early response protein 1R20; B-cell activation protein BL34; epididymis secretory protein Li 87; regulator of G-protein signalling 1; immediate-early response 1, B-cell specific; regulator of G-protein signaling 1; B-cell activation protein BL34; Early response protein 1R20
products gene name :
RGS1
other gene names :
RGS1; RGS1; 1R20; BL34; IER1; IR20; HEL-S-87; 1R20; BL34; IER1; RGS1
uniprot entry name :
RGS1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 25kDa band seen in HepG2 lysate. Recommended for use at 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-NLLNDLQANSLK, from the C Terminus of the protein sequence according to NP_002913.3.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425782
ncbi acc num :
NP_002913.3
ncbi gb acc num :
NM_002922.3
ncbi mol weight :
19,134 Da
ncbi pathways :
CXCR4-mediated Signaling Events Pathway 137910!!Calcium Regulation In The Cardiac Cell Pathway 198906!!G Alpha (i) Signalling Events Pathway 119550!!GPCR Downstream Signaling Pathway 119548!!Myometrial Relaxation And Contraction Pathways 198759!!Signal Transduction Pathway 477114!!Signaling By GPCR Pathway 106356
ncbi summary :
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008]