Goat anti-FOXC1 (C Term) Antibody | MyBioSource MBS420865 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-FOXC1 (C Term) Antibody

catalog :

MBS420865

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, zebrafish

application :

western blot, enzyme immunoassay, chromatin immunoprecipitation

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420865

products type :

Antibody

products full name :

Goat anti-FOXC1 (C Term) Antibody

products short name :

FOXC1

products name syn :

Goat Anti-FOXC1 (internal) Antibody; FOXC1; forkhead box C1; ARA; IGDA; IHG1; FKHL7; IRID1; FREAC3; iridogoniodysgenesis type 1; forkhead (Drosophila)-like 7; forkhead-related activator 3; Forkhead, drosophila, homolog-like 7; FREAC-3; RIEG3; forkhead/winged helix-like transcription factor 7; FOXC1 antibody; forkhead box C1 antibody; ARA antibody; IGDA antibody; IHG1 antibody; FKHL7 antibody; IRID1 antibody; FREAC3 antibody; iridogoniodysgenesis type 1 antibody; forkhead (Drosophila)-like 7 antibody; forkhead-related activator 3 antibody; Forkhead; drosophila; homolog-like 7 antibody; FREAC-3 antibody; RIEG3 antibody; forkhead/winged helix-like transcription factor 7 antibody; myeloid factor-delta antibody; FOXC1 (C Term)

other names :

forkhead box protein C1; Forkhead box protein C1; forkhead box protein C1; forkhead box C1; Forkhead-related protein FKHL7; Forkhead-related transcription factor 3; FREAC-3

products gene name :

FOXC1

other gene names :

FOXC1; FOXC1; ARA; IGDA; IHG1; FKHL7; IRID1; RIEG3; FREAC3; FREAC-3; FKHL7; FREAC3; FREAC-3

uniprot entry name :

FOXC1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Mouse, Zebrafish; Expected from sequence similarity: Human, Mouse

sequence length :

553

sequence :

RTSGAFVYDCSKF

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Chromatin Immunoprecipitation (ChIP)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 32000. Chromatin immunoprecipitation: Customer successfully used this antibody in ChIP from human cell line. This antibody has also been successfully described in a paper on zebrafish embryos (PubMed: 17000708).

other info1 :

Immunogen: Peptide with sequence RTSGAFVYDCSKF, from the C Terminus of the protein sequence according to NP_001444.2. Epitope: C Terminus

ncbi gi num :

119395716

ncbi acc num :

NP_001444.2

ncbi gb acc num :

NM_001453.2

ncbi mol weight :

56,789 Da

ncbi pathways :

Heart Development Pathway (198802)

ncbi summary :

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly. [provided by RefSeq, Jul 2008]

uniprot summary :

FOXC1: Binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Monomer. Expressed in all tissues and cell lines examined. Protein type: Cell development/differentiation; Cell cycle regulation; DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 6p25. Cellular Component: cytoplasm; nuclear heterochromatin; nucleoplasm; nucleus. Molecular Function: DNA bending activity; DNA binding; protein binding; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; transcription factor activity; transcription factor binding. Biological Process: artery morphogenesis; blood vessel remodeling; brain development; camera-type eye development; cardiac muscle cell proliferation; cell migration; cell proliferation; collagen fibril organization; embryonic heart tube development; eye development; germ cell migration; glycosaminoglycan metabolic process; heart development; in utero embryonic development; lacrimal gland development; lymph vessel development; mesenchymal cell development; negative regulation of angiogenesis; negative regulation of mitotic cell cycle; neural crest cell development; Notch signaling pathway; odontogenesis of dentine-containing teeth; ossification; ovarian follicle development; paraxial mesoderm formation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of blood vessel size; regulation of organ growth; regulation of transcription, DNA-dependent; skeletal development; somitogenesis; transcription from RNA polymerase II promoter; ureteric bud development; vascular endothelial growth factor receptor signaling pathway; ventricular cardiac muscle morphogenesis. Disease: Axenfeld-rieger Syndrome, Type 3; Iridogoniodysgenesis, Type 1

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage