catalog number :
MBS420861
products full name :
Goat anti-PLA2G1B Antibody
products short name :
PLA2G1B
products name syn :
PLA2G1B; phospholipase A2; group IB (pancreas); MGC119834; MGC119835; PLA2; PLA2A; PPLA2; phospholipase A2; group IB; PLA2G1B; phospholipase A2, group IB (pancreas); MGC119834; MGC119835; PLA2; PLA2A; PPLA2; phospholipase A2, group IB;
other names :
phospholipase A2; Phospholipase A2; phospholipase A2; phosphatidylcholine 2-acylhydrolase 1B; phospholipase A2, group IB (pancreas); Group IB phospholipase A2; Phosphatidylcholine 2-acylhydrolase 1B
products gene name :
PLA2G1B
other gene names :
PLA2G1B; PLA2G1B; PLA2; PLA2A; PPLA2; PLA2; PLA2A; PPLA2
uniprot entry name :
PA21B_HUMAN
sequence :
NKAHKNLDTKKYCQS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx. 17-18kDa band observed in Human Pancreas lysates (calculated MW of 16.4kDa according to NP_000919.1). In transfected HEK293 transiently expressing PLA2G1B a band of approx. 18kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.01ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence NKAHKNLDTKKYCQS, from the C Terminus of the protein sequence according to NP_000919.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425980
ncbi acc num :
NP_000919.1
ncbi gb acc num :
NM_000928.2
ncbi mol weight :
16,360 Da
ncbi pathways :
Acyl Chain Remodelling Of PC Pathway 645321!!Acyl Chain Remodelling Of PE Pathway 645317!!Acyl Chain Remodelling Of PG Pathway 645328!!Acyl Chain Remodelling Of PI Pathway 645326!!Acyl Chain Remodelling Of PS Pathway 645324!!Arachidonic Acid Metabolism Pathway 82991!!Arachidonic Acid Metabolism Pathway 366!!Ether Lipid Metabolism Pathway 82990!!Ether Lipid Metabolism Pathway 365!!Fat Digestion And Absorption Pathway 194385
ncbi summary :
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013]