antibody

Goat anti-14-3-3 tau/YWHAQ Antibody

MBS420856

0.1 mg

300 USD

polyclonal

goat

nonconjugated

human, mouse, rat, dog

western blot, enzyme immunoassay

Antibody

Goat anti-14-3-3 tau/YWHAQ Antibody

14-3-3 tau/YWHAQ

YWHAQ; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; 14-3-3; 1C5; HS1; 14-3-3 protein T-cell; 14-3-3 protein theta; protein tau; tyrosine 3/tryptophan 5 -monooxygenase activation protein, th; YWHAQ antibody; 14-3-3 protein tau antibody; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; theta polypeptide antibody; 14-3-3 antibody; 1C5 antibody; HS1 antibody; 14-3-3 protein T-cell antibody; 14-3-3 protein theta antibody; protein tau antibody; tyrosine 3/tryptophan 5 -monooxygenase activation protein; theta polypeptide antibody; 14-3-3 tau / YWHAQ

14-3-3 protein theta; 14-3-3 protein theta; 14-3-3 protein theta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1

YWHAQ

14-3-3 tau

YWHAQ; YWHAQ; 1C5; HS1; 14-3-3

1433T_HUMAN

Polyclonal

Goat

Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog

245

DDRKQTIDNSQ

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Peptide ELISA: Antibody detection limit dilution 1: 4000. Western Blot: Approx 28kDa band observed in Human Brain (Hippocampus) lysates (calculated MW of 27.8kDa according to NP_006817.1). Recommended concentration: 0. 03-0.1ug/ml.

Immunogen: Peptide with sequence C-DDRKQTIDNSQ, from the internal region of the protein sequence according to NP_006817.1. Epitope: Internal region

5803227

NP_006817.1

NM_006826.3

27,764 Da

Activation Of BAD And Translocation To Mitochondria Pathway (1270271); Activation Of BH3-only Proteins Pathway (1270270); Alpha6-Beta4 Integrin Signaling Pathway (198807); Apoptosis Pathway (1270262); Calcium Regulation In The Cardiac Cell Pathway (198906); Cell Cycle Pathway (1269741); Cell Cycle Checkpoints Pathway (1269742); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463)

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]

14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 2p25.1. Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; focal adhesion; membrane; mitochondrion; protein complex. Molecular Function: protein binding; protein C-terminus binding; protein domain specific binding; protein N-terminus binding. Biological Process: negative regulation of transcription, DNA-dependent; protein targeting; small GTPase mediated signal transduction; substantia nigra development

0.1 mg

300 USD