catalog number :
MBS420847
products full name :
Goat anti-ARHU / WRCH1 Antibody
products short name :
ARHU/WRCH1
products name syn :
RHOU; ras homolog gene family; member U; ARHU; WRCH1; hG28K; WRCH-1; CDC42L1; FLJ10616; DJ646B12.2; fJ646B12.2; 2310026M05Rik; ras homolog gene family; member U; Ryu GTPase; CDC42-like GTPase; GTP-binding protein like 1; Wnt-1 responsive Cdc42 homolog; FLJ10616; WRCH1; GTP-binding protein SB128; GTP-binding protein like 1; ras-like gene family member U; RHOU; ras homolog gene family, member U; ARHU; WRCH1; hG28K; WRCH-1; CDC42L1; FLJ10616; DJ646B12.2; fJ646B12.2; 2310026M05Rik; ras homolog gene family, member U; Ryu GTPase; CDC42-like GTPase; GTP-binding protein like 1; Wnt-1 responsive Cdc42 homolog; FLJ10616; WRCH1; GTP-binding protein SB128; GTP-binding protein like 1; ras-like gene family member U
other names :
rho-related GTP-binding protein RhoU; Rho-related GTP-binding protein RhoU; rho-related GTP-binding protein RhoU; RHOU; Ryu GTPase; 2310026M05Rik; CDC42-like GTPase 1; GTP-binding protein SB128; GTP-binding protein like 1; rho GTPase-like protein ARHU; ras-like gene family member U; wnt-1 responsive Cdc42 homolog 1; ras homolog gene family, member U; ras homolog family member U; CDC42-like GTPase 1; GTP-binding protein-like 1; Rho GTPase-like protein ARHU; Ryu GTPase; Wnt-1 responsive Cdc42 homolog 1; WRCH-1
products gene name :
RHOU
other gene names :
RHOU; RHOU; ARHU; G28K; WRCH1; hG28K; CDC42L1; WRCH-1
uniprot entry name :
RHOU_HUMAN
sequence :
PPQQGDPAFPDRCEA
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments gave an approx. 22kDa band in lysates of cell lines A431, HeLa and HEK293 after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 28.2kDa according to NP_067028.1. The 22kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence PPQQGDPAFPDRCEA, from the N Terminus of the protein sequence according to NP_067028.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426017
ncbi acc num :
NP_067028.1
ncbi gb acc num :
NM_021205.5
ncbi mol weight :
22,164 Da
ncbi pathways :
Rho GTPase Cycle Pathway 106503!!Signal Transduction Pathway 477114!!Signaling By Rho GTPases Pathway 106502
ncbi summary :
This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]