catalog number :
MBS420846
products full name :
Goat anti-PDE4D3 Antibody
products short name :
PDE4D3
products name syn :
Goat Anti-PDE4D Antibody; PDE4D3; phosphodiesterase 4D3; PDE4D3 antibody; phosphodiesterase 4D3 antibody
other names :
cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform PDE4D3; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; cAMP-specific 3',5'-cyclic phosphodiesterase 4D; phosphodiesterase 4D; DPDE3; PDE43
products gene name :
PDE4D
products gene name syn :
PDE4D3
other gene names :
PDE4D; PDE4D; DPDE3; PDE43; STRK1; ACRDYS2; HSPDE4D; PDE4DN2; DPDE3
uniprot entry name :
PDE4D_HUMAN
reactivity :
Tested: Rat; Expected from sequence similarity: Human, Rat, Pig
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 75kDa band observed in Rat Brain lysates (calculated MW of 76.5kDa according to human NP_006194.2). Recommended concentration: 0.01-0.03ug/ml.
other info1 :
Immunogen: Peptide with sequence HVNNFPFRRHS-C, from the N Terminus of the protein sequence according to NP_006194.2. Epitope: N Terminus
other info2 :
Note: This antibody is expected to recognize isoform 3 (NP_006194.2) only.
ncbi acc num :
NP_006194.2
ncbi gb acc num :
NM_006203.4
ncbi mol weight :
24,429 Da
ncbi pathways :
DARPP-32 Events Pathway (1269591); G Protein Signaling Pathways (198849); G Alpha (s) Signalling Events Pathway (1269575); GPCR Downstream Signaling Pathway (1269574); Morphine Addiction Pathway (552665); Morphine Addiction Pathway (554808); Myometrial Relaxation And Contraction Pathways (198759); Opioid Signalling Pathway (1269584); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307)
ncbi summary :
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.[provided by RefSeq, Sep 2009]