product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-SLC7A11 Antibody
catalog :
MBS420838
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, rat, dog
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420838
products type :
Antibody
products full name :
Goat anti-SLC7A11 Antibody
products short name :
SLC7A11
products name syn :
SLC7A11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; CCBR1; xCT; cystine/glutamate transporter; SLC7A11 antibody; solute carrier family 7; (cationic amino acid transporter; y+ system) member 11 antibody; CCBR1 antibody; xCT antibody; cystine/glutamate transporter antibody
other names :
cystine/glutamate transporter; Cystine/glutamate transporter; cystine/glutamate transporter; solute carrier family 7 member 11; Amino acid transport system xc-; Calcium channel blocker resistance protein CCBR1; Solute carrier family 7 member 11; xCT
products gene name :
SLC7A11
other gene names :
SLC7A11; SLC7A11; xCT; CCBR1
uniprot entry name :
XCT_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human, Rat; Expected from sequence similarity: Human, Dog
sequence length :
501
sequence :
KGQTQNFKDAFSGRD
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 50kDa band observed in Human Spleen and Human Thymus lysates (calculated MW of 55.4kDa according to NP_055146.1). Recommended concentration: 0. 02-0. 06ug/ml. An anonymous customer found positive results in WB on Rat spinal cord.
other info1 :
Immunogen: Peptide with sequence C-KGQTQNFKDAFSGRD, from the internal region of the protein sequence according to NP_055146.1. Epitope: Internal region
ncbi gi num :
7657683
ncbi acc num :
NP_055146.1
ncbi gb acc num :
NM_014331.3
ncbi mol weight :
55,423 Da
ncbi pathways :
Amino Acid Transport Across The Plasma Membrane Pathway (1269916); Basigin Interactions Pathway (1269376); Cell Surface Interactions At The Vascular Wall Pathway (1269373); Hemostasis Pathway (1269340); SLC-mediated Transmembrane Transport Pathway (1269907); Transmembrane Transport Of Small Molecules Pathway (1269903); Transport Of Inorganic Cations/anions And Amino Acids/oligopeptides Pathway (1269908)
ncbi summary :
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
uniprot summary :
SLC7A11: Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family. Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 4q28.3. Cellular Component: cell surface; cytoskeleton; integral to membrane; integral to plasma membrane; plasma membrane; rough endoplasmic reticulum. Molecular Function: cystine:glutamate antiporter activity; protein binding. Biological Process: amino acid transport; brain development; leukocyte migration; response to nicotine; response to oxidative stress; response to toxin
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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