Goat anti-AKT3 Antibody | MyBioSource MBS420828 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-AKT3 Antibody

catalog :

MBS420828

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420828

products type :

Antibody

products full name :

Goat anti-AKT3 Antibody

products short name :

AKT3

products name syn :

AKT3; PKBG; PRKBG; STK-2; RAC-gamma; RAC-PK-gamma; DKFZP434N0250; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma); protein kinase B gamma; serine threonine protein kinase, Akt-3; RAC-gamma serine/threonine protein kinase; PKB-GAMMA; AKT3 antibody; PKBG antibody; PRKBG antibody; STK-2 antibody; RAC-gamma antibody; RAC-PK-gamma antibody; DKFZP434N0250 antibody; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B; gamma) antibody; protein kinase B gamma antibody; serine threonine protein kinase; Akt-3 antibody; RAC-gamma serine/threonine protein kinase antibody

other names :

RAC-gamma serine/threonine-protein kinase isoform 1; RAC-gamma serine/threonine-protein kinase; RAC-gamma serine/threonine-protein kinase; AKT serine/threonine kinase 3; Protein kinase Akt-3; Protein kinase B gamma; PKB gamma; RAC-PK-gamma; STK-2

products gene name :

AKT3

other gene names :

AKT3; AKT3; MPPH; PKBG; MPPH2; PRKBG; STK-2; PKB-GAMMA; RAC-gamma; RAC-PK-gamma; PKBG; PKB gamma

uniprot entry name :

AKT3_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow

sequence length :

479

sequence :

CSPTSQIDNIGEEEM

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: A 50-55kDa band observed in lysates of cell lines HepG2 and Jurkat and in Mouse and Rat Brain lysates (calculated MW of 54. 0kDa according to NP_859029.1). Recommended concentration: 1-3ug/ml.

other info1 :

Immunogen: Peptide with sequence CSPTSQIDNIGEEEM, from the internal region of the protein sequence according to NP_005456.1; NP_859029.1. Epitope: Internal region

other info2 :

Note: This antibody is expected to recognise an epitope corresponding to aa 119-133 of both isoforms of human AKT3 protein. This antibody does not cross-react with human AKT1/2. Reported variants represent identical protein (NP_859029.1; NP_001193658.1).

ncbi gi num :

4885549

ncbi acc num :

NP_005456.1

ncbi gb acc num :

NM_005465.4

ncbi mol weight :

54,032 Da

ncbi pathways :

AGE-RAGE Signaling Pathway In Diabetic Complications (1319988); AGE-RAGE Signaling Pathway In Diabetic Complications (1319775); AKT Phosphorylates Targets In The Cytosol Pathway (1269189); AKT Phosphorylates Targets In The Nucleus Pathway (1269190); AKT-mediated Inactivation Of FOXO1A Pathway (1270342); AMPK Signaling Pathway (989139); AMPK Signaling Pathway (992181); Activation Of BAD And Translocation To Mitochondria Pathway (1270271); Activation Of BH3-only Proteins Pathway (1270270); Acute Myeloid Leukemia Pathway (83117)

ncbi summary :

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

uniprot summary :

Akt3: an AGC kinase that plays a critical role in controlling the balance between survival and apoptosis. Stimulated by platelet-derived growth factor, insulin, and insulin-like growth factor 1. Alternatively spliced isoforms have been described. Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, AGC; Kinase, protein; AGC group; AKT family. Chromosomal Location of Human Ortholog: 1q44. Cellular Component: cytoplasm; Golgi apparatus; intracellular; nucleoplasm; plasma membrane. Molecular Function: ATP binding; protein binding; protein kinase activity; protein serine/threonine kinase activity. Biological Process: mitochondrial genome maintenance; peptidyl-serine phosphorylation; protein amino acid phosphorylation; signal transduction. Disease: Megalencephaly-polymicrogyria-polydactyly-hydrocephalus Syndrome 2

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage