Goat anti-PPP2R5E Antibody | MyBioSource MBS420815 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-PPP2R5E Antibody

catalog :

MBS420815

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420815

products type :

Antibody

products full name :

Goat anti-PPP2R5E Antibody

products short name :

PPP2R5E

products name syn :

PPP2R5E; protein phosphatase 2, regulatory subunit B (B56), epsilon isoform; PP2A, B subunit, B' epsilon isoform; PP2A, B subunit, R5 epsilon isoform; PP2A, B subunit, B56 epsilon isoform; PP2A, B subunit, PR61 epsilon isoform; Serine/threonine protein ph; PPP2R5E antibody; protein phosphatase 2; regulatory subunit B (B56); epsilon isoform antibody; PP2A; B subunit; B 1 epsilon isoform antibody; PP2A; B subunit; R5 epsilon isoform antibody; PP2A; B subunit; B56 epsilon isoform antibody; PP2A; B subunit; PR61 epsilon isoform antibody; Serine/threonine protein phosphatase 2A; 56 kDa regulatory subunit; epsilon isoform antibody; protein phosphatase 2; regulatory subunit B 1; epsilon isoform antibody; PP2A; B subunit; R5 epsilon antibody; epsilon isoform of regulatory subunit B56; protein phosphatase 2A antibody; serine/threonine protein phosphatase 2A; 56 kDa regulatory subunit; epsilon antibody

other names :

serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform a; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; protein phosphatase 2 regulatory subunit B'epsilon; PP2A B subunit isoform B'-epsilon; PP2A B subunit isoform B56-epsilon; PP2A B subunit isoform PR61-epsilon; PP2A B subunit isoform R5-epsilon

products gene name :

PPP2R5E

other gene names :

PPP2R5E; PPP2R5E

uniprot entry name :

2A5E_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow

sequence length :

467

sequence :

LKRGLRRDGIIPT

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Approx 50kDa band observed in Human (Cerebellum), Mouse and Rat Brain lysates (calculated MW of 54.7kDa according to Human NP_001269108.1 and Mouse NP_036154.1 and 50.4kDa according to Rat NP_001100210.1). Recommended concentration: 0.1-0.3ug/ml.

other info1 :

Immunogen: Peptide with sequence C-LKRGLRRDGIIPT, from the C Terminus of the protein sequence according to NP_006237.1. Epitope: C Terminus

ncbi gi num :

5453956

ncbi acc num :

NP_006237.1

ncbi gb acc num :

NM_006246.3

ncbi mol weight :

46,180 Da

ncbi pathways :

AMER1 Mutants Destabilize The Destruction Complex Pathway (1268913); AMPK Signaling Pathway (989139); AMPK Signaling Pathway (992181); APC Truncation Mutants Have Impaired AXIN Binding Pathway (1268909); ARMS-mediated Activation Pathway (1269471); AXIN Missense Mutants Destabilize The Destruction Complex Pathway (1268912); AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway (1268910); Adaptive Immune System Pathway (1269171); Adrenergic Signaling In Cardiomyocytes Pathway (908257); Adrenergic Signaling In Cardiomyocytes Pathway (909696)

ncbi summary :

The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

uniprot summary :

PPP2R5E: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B56 family. Protein type: Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 14q23.1. Cellular Component: cytoplasm; protein phosphatase type 2A complex. Molecular Function: protein binding; protein phosphatase type 2A regulator activity. Biological Process: regulation of protein phosphatase type 2A activity; signal transduction

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage