catalog number :
MBS420809
products full name :
Goat anti-RPS19 Antibody
products short name :
RPS19
products name syn :
RPS19; ribosomal protein S19; HGNC:10402; DBA; 40S ribosomal protein S19; RPS19; ribosomal protein S19; HGNC:10402; DBA; 40S ribosomal protein S19
other names :
40S ribosomal protein S19; 40S ribosomal protein S19; 40S ribosomal protein S19; ribosomal protein S19
products gene name :
RPS19
other gene names :
RPS19; RPS19; DBA; S19; DBA1
uniprot entry name :
RS19_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 15kDa band observed in lysates of cell lines Daudi and K562 (calculated MW of 16.1kDa according to NP_001013.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-KMVEKDQDGGRK, from the internal region of the protein sequence according to NP_001013.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425717
ncbi acc num :
NP_001013.1
ncbi gb acc num :
NM_001022.3
ncbi mol weight :
16,060 Da
ncbi pathways :
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway 105970!!Cap-dependent Translation Initiation Pathway 105967!!Cytoplasmic Ribosomal Proteins Pathway 198853!!Disease Pathway 530764!!Eukaryotic Translation Elongation Pathway 105976!!Eukaryotic Translation Initiation Pathway 105966!!Eukaryotic Translation Termination Pathway 105978!!Formation Of A Pool Of Free 40S Subunits Pathway 105968!!Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway 105969!!GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway 105973
ncbi summary :
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]