catalog number :
MBS420808
products full name :
Goat anti-PPP2R5D Antibody
products short name :
PPP2R5D
products name syn :
PPP2R5D; MGC2134; MGC8949; protein phosphatase 2; regulatory subunit B (B56); delta isoform; PP2A; B subunit; B 1 delta isoform; PP2A; B subunit; R5 delta isoform; PP2A; B subunit; B56 delta isoform; PP2A; B subunit; PR61 delta isoform; Serine/threonine protein phosphatase 2A; 56 kDa regulatory subunit; delta isoform; protein phosphatase 2; regulatory subunit B 1; delta isoform; B56D; delta isoform of regulatory subunit B56; protein phosphatase 2A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; PPP2R5D; MGC2134; MGC8949; protein phosphatase 2, regulatory subunit B (B56), delta isoform; PP2A, B subunit, B' delta isoform; PP2A, B subunit, R5 delta isoform; PP2A, B subunit, B56 delta isoform; PP2A, B subunit, PR61 delta isoform; Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, delta isoform; protein phosphatase 2, regulatory subunit B', delta isoform; B56D; delta isoform of regulatory subunit B56, protein phosphatase 2A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform
other names :
serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform 1; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; PP2A B subunit isoform B'-delta; PP2A B subunit isoform R5-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A, B subunit, B' delta isoform; PP2A, B subunit, R5 delta isoform; PP2A, B subunit, B56 delta isoform; PP2A, B subunit, PR61 delta isoform; protein phosphatase 2, regulatory subunit B', delta isoform; protein phosphatase 2, regulatory subunit B (B56), delta isoform; Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, delta isoform; protein phosphatase 2, regulatory subunit B', delta; PP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta
products gene name :
PPP2R5D
other gene names :
PPP2R5D; PPP2R5D; B56D
uniprot entry name :
2A5D_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
sequence :
KRAEEFLTASQEAL
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 70kDa and 60kDa bands seen in 293 lysate (Predicted MW of 68kDa and 62kDa according to NP_006236 and AAH01175, respectively). Recommended for use at 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:20000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-KRAEEFLTASQEAL, from the C Terminus of the protein sequence according to NP_006236.1; NP_851307.1; NP_851308.1. Corresponding Immunizing Peptide: Catalog #MBS426258
other info2 :
Important Note: This antibody is expected to recognise all three reported isoforms (NP_006236.1; NP_851307.1; NP_851308.1).
ncbi acc num :
NP_006236.1
ncbi gb acc num :
NM_006245.3
ncbi mol weight :
58,453 Da
ncbi pathways :
AMER1 Mutants Destabilize The Destruction Complex Pathway 1016198!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!APC Truncation Mutants Are Not K63 Polyubiquitinated Pathway 1016193!!APC Truncation Mutants Have Impaired AXIN Binding Pathway 1016194!!AXIN Missense Mutants Destabilize The Destruction Complex Pathway 1016197!!AXIN Mutants Destabilize The Destruction Complex, Activating WNT Signaling Pathway 1016195!!Activated TLR4 Signalling Pathway 106400!!Adaptive Immune System Pathway 366160!!Adrenergic Signaling In Cardiomyocytes Pathway 908257
ncbi summary :
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]