Goat anti-MAOB Antibody | MyBioSource MBS420806 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-MAOB Antibody

catalog :

MBS420806

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420806

products type :

Antibody

products full name :

Goat anti-MAOB Antibody

products short name :

MAOB

products name syn :

MAOB; monoamine oxidase B; HGNC: 6834; MGC26382; RP1-201D17__B.1; MAO, brain; MAO, platelet; adrenalin oxidase; amine oxidase (flavin-containing); tyramine oxidase; MAOB antibody; monoamine oxidase B antibody; HGNC: 6834 antibody; MGC26382 antibody; RP1-201D17__B.1 antibody; MAO; brain antibody; MAO; platelet antibody; adrenalin oxidase antibody; amine oxidase (flavin-containing) antibody; tyramine oxidase antibody

other names :

amine oxidase; Amine oxidase [flavin-containing] B; amine oxidase [flavin-containing] B; monoamine oxidase B; Monoamine oxidase type B; MAO-B

products gene name :

MAOB

other gene names :

MAOB; MAOB; MAO-B

uniprot entry name :

AOFB_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow

sequence length :

520

sequence :

HKARKLARLTKEE

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), ELISA (EIA)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 60kDa band observed in Human Brain (Hippocampus) lysates (calculated MW of 58.8kDa according to NP_000889.3). Recommended concentration: 0.5-1.5ug/ml. Enzyme immunoassay: Sandwich-type ELISA with increasing amount of recombinant MAOB captured by a rabbit antibody. Recommended reporter concentration: 0.5-1ug/ml.

other info1 :

Immunogen: Peptide with sequence C-HKARKLARLTKEE, from the internal region of the protein sequence according to NP_000889.3. Epitope: Internal region

other info2 :

Note: This antibody is not expected to cross-react with MAOA.

ncbi gi num :

38202207

ncbi acc num :

NP_000889.3

ncbi gb acc num :

NM_000898.4

ncbi mol weight :

46,539 Da

ncbi pathways :

Alcoholism Pathway (585563); Alcoholism Pathway (587116); Alpha-synuclein Signaling Pathway (137913); Amine Oxidase Reactions Pathway (1270203); Amphetamine Addiction Pathway (547607); Amphetamine Addiction Pathway (550546); Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Biogenic Amines Are Oxidatively Deaminated To Aldehydes By MAOA And MAOB Pathway (1270204); Biological Oxidations Pathway (1270189)

ncbi summary :

The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]

uniprot summary :

MAOB: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine. Belongs to the flavin monoamine oxidase family. Protein type: Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - histidine; Mitochondrial; Amino Acid Metabolism - phenylalanine; Oxidoreductase; Membrane protein, integral; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - glycine, serine and threonine; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - tryptophan; EC 1.4.3.4. Chromosomal Location of Human Ortholog: Xp11.23. Cellular Component: integral to membrane; mitochondrial envelope; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion. Molecular Function: amine oxidase activity; electron carrier activity; FAD binding; protein homodimerization activity. Biological Process: dopamine catabolic process; hydrogen peroxide biosynthetic process; negative regulation of serotonin secretion; positive regulation of dopamine metabolic process; response to aluminum ion; response to corticosterone stimulus; response to drug; response to ethanol; response to lipopolysaccharide; response to selenium ion; response to toxin; substantia nigra development

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage