catalog number :
MBS420764
products full name :
Goat anti-Orexin Receptor 2 Antibody
products short name :
Orexin Receptor 2
products name syn :
OTTHUMP00000039969; hypocretin (orexin) receptor 2; HCRTR2; OX2R; hypocretin receptor-2; orexin receptor 2; Goat Anti-Orexin Receptor 2 (aa405-419); OTTHUMP00000039969; hypocretin (orexin) receptor 2; HCRTR2; OX2R; hypocretin receptor-2; orexin receptor 2
other names :
orexin receptor 2; Orexin receptor type 2; orexin receptor type 2; ox2-R; ox-2-R; orexin type-2 receptor; hypocretin receptor type 2; hypocretin (orexin) receptor 2; Hypocretin receptor type 2
products gene name :
HCRTR2
other gene names :
HCRTR2; HCRTR2; OX2R; Ox-2-R; Ox2-R; Ox2R
uniprot entry name :
OX2R_HUMAN
reactivity :
Human, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 50kDa band observed in human brain (cerebral cortex, hippocampus and substantia nigra) lysates (calculated MW of 50.7kDa according to NP_001517.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence SGTKLEDSPPCRN, from the N Terminus of the protein sequence according to NP_001517.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428444
ncbi acc num :
NP_001517.1
ncbi gb acc num :
NM_001526.2
ncbi mol weight :
50,694 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Class A Rhodopsin-like Pathway 198886!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462!!Orexin And Neuropeptides FF And QRFP Bind To Their Respective Receptors Pathway 106362!!Peptide Ligand-binding Receptors Pathway 106358
ncbi summary :
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]