catalog number :
MBS420751
products full name :
Goat anti-UBE2L3 Antibody
products short name :
UBE2L3
products name syn :
UBE2L3; ubiquitin-conjugating enzyme E2L 3; UBCH7; E2-F1; L-UBC; UbcM4; ubiquitin carrier protein; ubiquitin-conjugating enzyme UBCH7; ubiquitin-protein ligase; UBE2L3; ubiquitin-conjugating enzyme E2L 3; UBCH7; E2-F1; L-UBC; UbcM4; ubiquitin carrier protein; ubiquitin-conjugating enzyme UBCH7; ubiquitin-protein ligase
other names :
ubiquitin-conjugating enzyme E2 L3 isoform 1; Ubiquitin-conjugating enzyme E2 L3; ubiquitin-conjugating enzyme E2 L3; ubiquitin-protein ligase L3; ubiquitin carrier protein L3; ubiquitin-conjugating enzyme E2-F1; ubiquitin-conjugating enzyme UBCH7; ubiquitin-conjugating enzyme E2L 3; L-UBC; UbcH7; Ubiquitin carrier protein L3; Ubiquitin-conjugating enzyme E2-F1; Ubiquitin-protein ligase L3
products gene name :
UBE2L3
other gene names :
UBE2L3; UBE2L3; E2-F1; L-UBC; UBCH7; UbcM4; UBCE7; UBCH7
uniprot entry name :
UB2L3_HUMAN
reactivity :
Human, Mouse, Cow, Rat
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 18kDa band observed in lysates of cell lines HeLa and Jurkat and also in lysates of Mouse and Rat Skeletal muscle and Testis (calculated MW of 17.9kDa according to Human NP_003338.1 and Mouse NP_033482.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-EFTKKYGEKRPVD, from the C Terminus of the protein sequence according to NP_003338.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425349
ncbi acc num :
NP_003338.1
ncbi gb acc num :
NM_003347.3
ncbi mol weight :
24,004 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Alpha-synuclein Signaling Pathway 137913!!Antigen Processing: Ubiquitination Proteasome Degradation Pathway 366162!!BARD1 Signaling Events Pathway 137959!!Class I MHC Mediated Antigen Processing Presentation Pathway 366161!!Immune System Pathway 106386!!Parkin-Ubiquitin Proteasomal System Pathway 700638!!Parkinson's Disease Pathway 83098!!Parkinsons Disease Pathway 705377!!Ubiquitin Mediated Proteolysis Pathway 83056
ncbi summary :
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]