catalog number :
MBS420745
products full name :
Goat anti-TRPV5 Antibody
products short name :
TRPV5
products name syn :
TRPV5; transient receptor potential cation channel; subfamily V; member 5; CAT2; ECAC1; OTRPC3; calcium transporter 2; epithelial calcium channel 1; osm-9-like TRP channel 3; TRPV5; transient receptor potential cation channel, subfamily V, member 5; CAT2; ECAC1; OTRPC3; calcium transporter 2; epithelial calcium channel 1; osm-9-like TRP channel 3
other names :
transient receptor potential cation channel subfamily V member 5; Transient receptor potential cation channel subfamily V member 5; transient receptor potential cation channel subfamily V member 5; calcium transporter 2; osm-9-like TRP channel 3; calcium transport protein 2; epithelial calcium channel 1; transient receptor potential cation channel, subfamily V, member 5; Calcium transport protein 2; CaT2; Epithelial calcium channel 1; ECaC; ECaC1; Osm-9-like TRP channel 3; OTRPC3
products gene name :
TRPV5
other gene names :
TRPV5; TRPV5; CAT2; ECAC1; OTRPC3; ECAC1; TrpV5; CaT2; ECaC; ECaC1; OTRPC3
uniprot entry name :
TRPV5_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
app notes :
Western Blot: Approx 85kDa band observed in Human Pancreas lysates (calculated MW of 82.6kDa according to NP_062815.2). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000. Immunocytochemsitry/Immunofluorescence: This antibody has been successfully used in ICC/IF for human retinal pigment epithelium as described in the following paper: Kennedy et al, Mol Vis. 2010 Apr 14;16:665-75; PMID: 20405023.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-SHRGWEILRQNT, from the internal region of the protein sequence according to NP_062815.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426896
ncbi acc num :
NP_062815.2
ncbi gb acc num :
NM_019841.5
ncbi mol weight :
43,186 Da
ncbi pathways :
Endocrine And Other Factor-regulated Calcium Reabsorption Pathway 213307!!Endocrine And Other Factor-regulated Calcium Reabsorption Pathway 213276!!Ion Channel Transport Pathway 187193!!Osteoclast Signaling Pathway 198769!!Stimuli-sensing Channels Pathway 771568!!TRP Channels Pathway 906028!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level. [provided by RefSeq, Jul 2008]