Goat anti-CPT1A Antibody | MyBioSource MBS420742 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-CPT1A Antibody

catalog :

MBS420742

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420742

products type :

Antibody

products full name :

Goat anti-CPT1A Antibody

products short name :

CPT1A

products name syn :

CPT1A; carnitine palmitoyltransferase 1A (liver); CPT1; CPT1-L; L-CPT1; carnitine palmitoyltransferase 1A; carnitine palmitoyltransferase I; carnitine palmitoyltransferase I, liver; CPT1A antibody; carnitine palmitoyltransferase 1A (liver) antibody; CPT1 antibody; CPT1-L antibody; L-CPT1 antibody; carnitine palmitoyltransferase 1A antibody; carnitine palmitoyltransferase I antibody; carnitine palmitoyltransferase I; liver antibody

other names :

carnitine O-palmitoyltransferase 1, liver isoform isoform 1; Carnitine O-palmitoyltransferase 1, liver isoform; carnitine O-palmitoyltransferase 1, liver isoform; carnitine palmitoyltransferase 1A; Carnitine O-palmitoyltransferase I, liver isoform; CPT I; CPTI-L; Carnitine palmitoyltransferase 1A

products gene name :

CPT1A

other gene names :

CPT1A; CPT1A; CPT1; CPT1-L; L-CPT1; CPT1; CPT1-L; CPT I; CPTI-L

uniprot entry name :

CPT1A_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human

sequence length :

773

sequence :

DPAQTVEQRLKLFK

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 128000. Immunohistochemistry: In paraffin embedded Human Kidney shows mitochindrial staining in PCT. Recommended concentration, 4-6ug/ml. Western Blot: Approx 80kDa band observed in human liver lysates (calculated MW of 86.2kDa according to NP_001027017.1). Recommended concentration: 0.1-0.3ug/ml.

other info1 :

Immunogen: Peptide with sequence C-DPAQTVEQRLKLFK, from the internal region of the protein sequence according to NP_001867.2; NP_001027017.1. Epitope: Internal region

other info2 :

Note: This antibody is expected to recognize both reported isoforms (NP_001867.2; NP_001027017.1) but is not expected to recognise CPT1B.

ncbi gi num :

73623030

ncbi acc num :

NP_001867.2

ncbi gb acc num :

NM_001876.3

ncbi mol weight :

86,239 Da

ncbi pathways :

AMPK Signaling Pathway (198868); AMPK Signaling Pathway (989139); AMPK Signaling Pathway (992181); Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); Circadian Clock Pathway (1269871); FOXA2 And FOXA3 Transcription Factor Networks Pathway (137911); Fatty Acid Beta Oxidation Pathway (198865); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296)

ncbi summary :

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

CPT1A: Belongs to the carnitine/choline acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Membrane protein, multi-pass; Lipid Metabolism - fatty acid; EC 2.3.1.21; Mitochondrial; Transferase. Chromosomal Location of Human Ortholog: 11q13.2. Cellular Component: integral to mitochondrial outer membrane; membrane; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion. Molecular Function: carnitine O-palmitoyltransferase activity; identical protein binding. Biological Process: carnitine metabolic process; carnitine shuttle; circadian rhythm; eating behavior; epithelial cell differentiation; fatty acid beta-oxidation; glucose metabolic process; long-chain fatty acid metabolic process; positive regulation of fatty acid beta-oxidation; protein homooligomerization; regulation of insulin secretion; response to drug; response to organic cyclic substance; triacylglycerol metabolic process. Disease: Carnitine Palmitoyltransferase I Deficiency

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage