antibody

Goat anti-BMPR1A Antibody

MBS420733

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, dog

western blot, enzyme immunoassay

Antibody

Goat anti-BMPR1A Antibody

BMPR1A

BMPR1A; bone morphogenetic protein receptor; type IA; HGNC:1076; ACVRLK3; ALK3; activin A receptor; type II-like kinase 3; BMPR1A; bone morphogenetic protein receptor, type IA; HGNC:1076; ACVRLK3; ALK3; activin A receptor, type II-like kinase 3

bone morphogenetic protein receptor type-1A; Bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor type-1A; ALK-3; BMPR-1A; BMP type-1A receptor; activin receptor-like kinase 3; activin A receptor, type II-like kinase 3; serine/threonine-protein kinase receptor R5; bone morphogenetic protein receptor, type IA; Activin receptor-like kinase 3; ALK-3; Serine/threonine-protein kinase receptor R5; SKR5; CD_antigen: CD292

BMPR1A

BMPR1A; BMPR1A; ALK3; SKR5; CD292; ACVRLK3; 10q23del; ACVRLK3; ALK3; BMP type-1A receptor; BMPR-1A; ALK-3; SKR5

BMR1A_HUMAN

Polyclonal

Goat

Human, Dog

532

KSDSDQKKSEN

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Approx 60kDa band observed in lysates of cell lines HeLa and HepG2 (calculated MW of 60.2kDa according to NP_004320.2). Recommended concentration: 1-3ug/ml. An additional band of 20kDa was consistently observed, however this band was not blocked by the immunizing peptide and it is therefore a non-specific signal. We call for caution when used for other assays than Western blot. Peptide ELISA: antibody detection limit dilution 1:16000.

Epitope: Internal Region. Immunogen: Peptide with sequence C-KSDSDQKKSEN, from the internal region of the protein sequence according to NP_004320.2.

Corresponding Immunizing Peptide: Catalog #MBS425470

41349437

NP_004320.2

NM_004329.2

60,198 Da

BMP Signalling And Regulation Pathway 198910!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Endochondral Ossification Pathway 198812!!Heart Development Pathway 198802!!Hippo Signaling Pathway 749777!!Hippo Signaling Pathway 750388!!Integrated Breast Cancer Pathway 219801!!Signal Transduction Pathway 477114!!Signaling By BMP Pathway 106336

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD