product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-SNM1/DCLRE1A (internal) Antibody
catalog :
MBS420731
quantity :
0.1 mg
price :
225 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420731
products type :
Antibody
products full name :
Goat anti-SNM1/DCLRE1A (internal) Antibody
products short name :
SNM1/DCLRE1A
products name syn :
Goat Anti-SNM1 (C Term) Antibody; DCLRE1A; DNA cross-link repair 1A (PSO2 homolog, S. cerevisiae); HGNC: 17660; KIAA0086; PSO2; SNM1; DNA-crosslink repair gene SNM1; SNM1A; DNA cross-link repair 1A; OTTHUMP00000020516; DCLRE1A antibody; DNA cross-link repair 1A (PSO2 homolog; S. cerevisiae) antibody; HGNC: 17660 antibody; KIAA0086 antibody; PSO2 antibody; SNM1 antibody; DNA-crosslink repair gene SNM1 antibody; SNM1A antibody; DNA cross-link repair 1A antibody; OTTHUMP00000020516 antibody; SNM1 / DCLRE1A (internal)
other names :
DNA cross-link repair 1A protein; DNA cross-link repair 1A protein; DNA cross-link repair 1A protein; DNA cross-link repair 1A; SNM1 homolog A; hSNM1; hSNM1A
products gene name :
DCLRE1A
products gene name syn :
SNM1
other gene names :
DCLRE1A; DCLRE1A; PSO2; SNM1; SNM1A; KIAA0086; SNM1; SNM1A; hSNM1; hSNM1A
uniprot entry name :
DCR1A_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Expected from sequence similarity: Human
sequence length :
1040
sequence :
PSPNQKRSSQCKRK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 8000. Western Blot: Preliminary experiments gave an approx 26kDa band in human duodenum lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 117kDa according to NP_055696.2. The 26kDa band was successfully blocked by incubation with the immunizing peptide.
other info1 :
Immunogen: Peptide with sequence PSPNQKRSSQCKRK, from the internal region of the protein sequence according to NP_055696.3. Epitope: Internal region
ncbi gi num :
223278374
ncbi acc num :
NP_055696.3
ncbi gb acc num :
NM_014881.4
ncbi mol weight :
116,400 Da
ncbi pathways :
DNA Repair Pathway (1270350); Fanconi Anemia Pathway (1309121)
ncbi summary :
This gene encodes a conserved protein that is involved in the repair of DNA interstrand cross-links. DNA cross-links suppress transcription, replication, and DNA segregation. The encoded protein is a regulator of the mitotic cell cycle checkpoint. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
uniprot summary :
DCLRE1A: May be required for DNA interstrand cross-link repair. Also required for checkpoint mediated cell cycle arrest in early prophase in response to mitotic spindle poisons. Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family. Chromosomal Location of Human Ortholog: 10q25.1. Cellular Component: nuclear chromosome, telomeric region; nucleolus; nucleoplasm; nucleus. Molecular Function: 5'-3' exodeoxyribonuclease activity; damaged DNA binding. Biological Process: cell division; double-strand break repair via nonhomologous end joining; mitosis; protection from non-homologous end joining at telomere
size1 :
0.1 mg
price1 :
225 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
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