catalog number :
MBS420725
products full name :
Goat anti-S100A4/CAPL Antibody
products short name :
S100A4/CAPL
products name syn :
S100A4; CAPL; S100 calcium binding protein A4; 18A2; 42A; MTS1; P9KA; PEL98; S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog); S100 calcium-binding protein A4; S100 calcium-binding protein A4 (calcium pr; S100A4 antibody; CAPL antibody; S100 calcium binding protein A4 antibody; 18A2 antibody; 42A antibody; MTS1 antibody; P9KA antibody; PEL98 antibody; S100 calcium binding protein A4 (calcium protein; calvasculin; metastasin; murine placental homolog) antibody; S100 calcium-binding protein A4 antibody; S100 calcium-binding protein A4 (calcium protein; calvasculin; metastasin; murine placental homolog) antibody; malignant transformation suppression 1 antibody; S100A4 / CAPL
other names :
protein S100-A4; Protein S100-A4; protein S100-A4; S100 calcium binding protein A4; Calvasculin; Metastasin; Placental calcium-binding protein; Protein Mts1; S100 calcium-binding protein A4
products gene name :
S100A4
products gene name syn :
CAPL
other gene names :
S100A4; S100A4; 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98; CAPL; MTS1
uniprot entry name :
S10A4_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000. Immunohistochemistry: In paraffin embedded Human Small Intestine shows staining of lymphatic cells in the lamina propria. Recommended concentration, 1-2ug/ml. Western Blot: Approx 13kDa band observed in Human Peripheral blood mononuclear cells lysates (calculated MW of 11.7kDa according to NP_002952.1). Recommended concentration: 0. 05-0.2ug/ml.
other info1 :
Immunogen: Peptide with sequence CNEFFEGFPDKQP, from the C Terminus of the protein sequence according to NP_002952.1; NP_062427.1. Epitope: C Terminus
other info2 :
Note: Both variants (NP_002952.1; NP_062427.1) represent identical protein.
ncbi acc num :
NP_002952.1
ncbi gb acc num :
NM_002961.2
ncbi mol weight :
11,729 Da
ncbi summary :
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
S100A4: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]. Protein type: Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: extracellular space; neuron projection; nucleus; perinuclear region of cytoplasm. Molecular Function: actin binding; calcium ion binding; calcium-dependent protein binding; identical protein binding; protein binding; RAGE receptor binding. Biological Process: epithelial to mesenchymal transition; positive regulation of I-kappaB kinase/NF-kappaB cascade