catalog number :
MBS420721
products full name :
Goat anti-ACOX2 (Human) Antibody
products short name :
ACOX2
products name syn :
ACOX2; acyl-Coenzyme A oxidase 2; branched chain; BCOX; BRCACOX; BRCOX; THCCox; Peroxisomal branched chain acyl-CoA oxidase; THCA-CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase; Goat Anti-ACOX2; acyl-Coenzyme A oxidase 2, branched chain; BCOX; BRCACOX; BRCOX; THCCox; Peroxisomal branched chain acyl-CoA oxidase; THCA-CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase
other names :
peroxisomal acyl-coenzyme A oxidase 2; Peroxisomal acyl-coenzyme A oxidase 2; peroxisomal acyl-coenzyme A oxidase 2; THCA-CoA oxidase; trihydroxycoprostanoyl-CoA oxidase; acyl-Coenzyme A oxidase 2, branched chain; peroxisomal branched chain acyl-CoA oxidase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; acyl-CoA oxidase 2, branched chain; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase; THCA-CoA oxidase; THCCox
products gene name :
ACOX2
other gene names :
ACOX2; ACOX2; BCOX; BRCOX; THCCox; BRCACOX; THCA-CoA oxidase; THCCox
uniprot entry name :
ACOX2_HUMAN
reactivity :
Human, Rabbit
sequence :
QWAQKSPTNTQENP
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 75kDa band observed in Human Liver lysates (calculated MW of 76.8kDa according to NP_003491.1). Recommended concentration: 0.5-1.5ug/ml.
An additional band of 37kDa was consistently observed, however this band was not blocked by the immunizing peptide and it is therefore a non-specific signal. We call for caution when used for other assays than Western blot. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: Internal Region (Near the C Terminus). Immunogen: Peptide with sequence C-QWAQKSPTNTQENP, from the internal region (near the C Terminus) of the protein sequence according to NP_003491.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428508
ncbi acc num :
NP_003491.1
ncbi gb acc num :
NM_003500.3
ncbi mol weight :
76,827 Da
ncbi pathways :
Beta-oxidation Of Pristanoyl-CoA Pathway 106138!!Bile Acid And Bile Salt Metabolism Pathway 106144!!Bile Acid Biosynthesis, Cholesterol = Cholate/chenodeoxycholate Pathway 413432!!Bile Acid Biosynthesis, Cholesterol = Cholate/chenodeoxycholate Pathway 468297!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!PPAR Signaling Pathway 83042!!PPAR Signaling Pathway 450!!Peroxisomal Lipid Metabolism Pathway 106136
ncbi summary :
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq, Mar 2009]