product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Hamartin / TSC1 (isoform 1) Antibody
catalog :
MBS420710
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, immunohistochemistry, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS420710
products type :
Antibody
products full name :
Goat anti-Hamartin / TSC1 (isoform 1) Antibody
products short name :
Hamartin/TSC1
products name syn :
TSC1; hamartin; tuberous sclerosis 1; HGNC:12362; KIAA0243; LAM; MGC86987; TSC; tuberous sclerosis 1 protein; tumor suppressor; TSC1; hamartin; tuberous sclerosis 1; HGNC:12362; KIAA0243; LAM; MGC86987; TSC; tuberous sclerosis 1 protein; tumor suppressor
other names :
hamartin isoform 1; Hamartin; hamartin; tumor suppressor; tuberous sclerosis 1 protein; tuberous sclerosis 1; Tuberous sclerosis 1 protein
products gene name :
TSC1
other gene names :
TSC1; TSC1; LAM; TSC; KIAA0243; TSC
uniprot entry name :
TSC1_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog
sequence length :
1164
sequence :
QLHIMDYNETHHEH
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Uterus shows membranous staining around non-basal nuclei and at the lumen of the endometrial gland. Recommended concentration, 3-6ug/ml. Western Blot: Approx 150kDa band observed in Human Brain lysates (calculated MW of 130kDa according to NP_000359.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Miloloza et al Hum Mol Genet. 2000 Jul 22;9(12):1721-7; PMID: 10915759). In transfected HEK293 transiently expressing Human TSC1 a band of approx. 120kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-QLHIMDYNETHHEH, from the C Terminus of the protein sequence according to NP_000359.1. Corresponding Immunizing Peptide: Catalog #MBS426893
other info2 :
Important Note: This antibody is expected to recognise isoform 1 (NP_000359.1) only.
ncbi gi num :
4507693
ncbi acc num :
NP_000359.1
ncbi gb acc num :
NM_000368.4
ncbi mol weight :
124,015 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Energy Dependent Regulation Of MTOR By LKB1-AMPK Pathway 160972!!IGF1R Signaling Cascade Pathway 730346!!IRS-mediated Signalling Pathway 106426!!IRS-related Events Pathway 106424!!IRS-related Events Triggered By IGF1R Pathway 730348!!Inhibition Of TSC Complex Formation By PKB Pathway 106431!!Insulin Signaling Pathway 198845
ncbi summary :
This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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