catalog number :
MBS420703
products full name :
Goat anti-KF1 / ZFP103 Antibody
products short name :
KF1/ZFP103
products name syn :
RNF103; KF1; hkf-1; ZFP103; RNF103;; ring finger protein 103; zinc finger protein 103 homolog (mouse); Zinc finger protein expressed in cerebellum; zinc finger protein homologous to Zfp103 in mouse; MGC102815; MGC41857; zinc finger protein 103 homolog; RNF103; KF1; hkf-1; ZFP103; RNF103,; ring finger protein 103; zinc finger protein 103 homolog (mouse); Zinc finger protein expressed in cerebellum; zinc finger protein homologous to Zfp103 in mouse; MGC102815; MGC41857; zinc finger protein 103 homolog
other names :
E3 ubiquitin-protein ligase RNF103 isoform 1; E3 ubiquitin-protein ligase RNF103; E3 ubiquitin-protein ligase RNF103; zinc finger protein 103 homolog; zinc finger protein expressed in cerebellum; ring finger protein 103; KF-1; hKF-1; RING finger protein 103; Zinc finger protein 103 homolog; Zfp-103
products gene name :
RNF103
other gene names :
RNF103; RNF103; KF1; KF-1; HKF-1; ZFP103; ZFP-103; ZFP103; hKF-1; Zfp-103
uniprot entry name :
RN103_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Approx. 35kDa and 60kDa bands observed in Human Brain and Human Liver lysates at 1ug of primary. Please note that the band we observe is different from the predicted size of approx. 79kDa according to NP_005658. Currently we cannot find an explanation for this in the literature. Have any splice variants/modified forms been reported?. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-YAQHQPLSNDVPS, from the C Terminus of the protein sequence according to NP_005658.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425348
ncbi acc num :
NP_005658.1
ncbi gb acc num :
NM_005667.3
ncbi mol weight :
79,405 Da
ncbi summary :
The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011]