Goat anti-SRD5A1/5-alpha reductase 1 Antibody | MyBioSource MBS420692 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-SRD5A1/5-alpha reductase 1 Antibody

catalog :

MBS420692

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS420692

products type :

Antibody

products full name :

Goat anti-SRD5A1/5-alpha reductase 1 Antibody

products short name :

SRD5A1/5-alpha reductase 1

products name syn :

Goat Anti-SRD5A1 Antibody; SRD5A1; steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1); 5-alpha reductase; steroid 5-alpha-reductase type I; 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1; steroid-5-alpha-reductase 1; SRD5A1 antibody; steroid-5-alpha-reductase; alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) antibody; 5-alpha reductase antibody; steroid 5-alpha-reductase type I antibody; 3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1 antibody; steroid-5-alpha-reductase 1 antibody; 5-alpha reductase 1; SRD5A1 / 5-alpha reductase 1

other names :

3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform 1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; 3-oxo-5-alpha-steroid 4-dehydrogenase 1; steroid 5 alpha-reductase 1; SR type 1; Steroid 5-alpha-reductase 1; S5AR 1

products gene name :

SRD5A1

other gene names :

SRD5A1; SRD5A1; S5AR 1; S5AR 1

uniprot entry name :

S5A1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human

sequence length :

259

sequence :

ATATGVAEERLLC

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Immunohistochemistry (IHC)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 64000. Immunohistochemistry: In paraffin embedded Human Prostate shows reticulate staining in the cytoplasm of secretory cells in the gland. Recommended concentration, 4-6ug/ml.

other info1 :

Immunogen: Peptide with sequence ATATGVAEERLLC, from the N Terminus of the protein sequence according to NP_001038.1. Epitope: N Terminus

ncbi gi num :

4507201

ncbi acc num :

NP_001038.1

ncbi gb acc num :

NM_001047.3

ncbi mol weight :

29,459 Da

ncbi pathways :

Androgen Biosynthesis Pathway (1270050); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001); Metabolism Of Steroid Hormones Pathway (1270046); Steroid Hormone Biosynthesis Pathway (82940); Steroid Hormone Biosynthesis Pathway (301); Allopregnanolone Biosynthesis Pathway (1108771); Allopregnanolone Biosynthesis Pathway (1108836); Androgen Biosynthesis Pathway (545302); Androgen Biosynthesis Pathway (545459)

ncbi summary :

Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]

uniprot summary :

SRD5A1: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. Belongs to the steroid 5-alpha reductase family. Protein type: Membrane protein, integral; EC 1.3.1.22; Membrane protein, multi-pass; Lipid Metabolism - androgen and estrogen; Oxidoreductase. Chromosomal Location of Human Ortholog: 5p15. Cellular Component: cell soma; endoplasmic reticulum membrane; integral to membrane; myelin sheath; perinuclear region of cytoplasm. Molecular Function: 3-oxo-5-alpha-steroid 4-dehydrogenase activity; amide binding; cholestenone 5-alpha-reductase activity; electron carrier activity. Biological Process: androgen biosynthetic process; cell differentiation; cellular response to insulin stimulus; cellular response to starvation; cerebral cortex development; circadian sleep/wake cycle, REM sleep; diterpenoid metabolic process; female genitalia development; hippocampus development; hypothalamus development; liver development; male genitalia development; male gonad development; pituitary gland development; progesterone metabolic process; response to drug; response to follicle-stimulating hormone stimulus; response to muscle activity; serotonin metabolic process; sex determination; spinal cord development; thalamus development; urogenital system development

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage