This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Ymer / CCDC50 Antibody
catalog :
MBS420644
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, dog
application :
western blot, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS420644
products type :
Antibody
products full name :
Goat anti-Ymer / CCDC50 Antibody
products short name :
Ymer/CCDC50
products name syn :
Ymer protein; coiled-coil domain containing 50; C3orf6; YMER; C3orf6; chromosome 3 open reading frame 6; CCDC50; Ymer protein; coiled-coil domain containing 50; C3orf6, YMER; C3orf6; chromosome 3 open reading frame 6; DFNA44
other names :
coiled-coil domain-containing protein 50 long isoform; Coiled-coil domain-containing protein 50; coiled-coil domain-containing protein 50; protein Ymer; coiled-coil domain containing 50; Protein Ymer
products gene name :
CCDC50
other gene names :
CCDC50; CCDC50; YMER; C3orf6; DFNA44; C3orf6
uniprot entry name :
CCD50_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Rat, Dog, Cow
sequence length :
482
sequence :
CFSKSESSHKGFHYK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Pancreas shows strong staining in cytoplasm in select acinar cells. Recommended concentration, 5-10ug/ml. Western Blot: Preliminary experiments gave an approx 18kDa band in Human Brain lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 56.3kDa according to NP_848018.1 and 35.8kDa according to NP_777568.1. The 18kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence CFSKSESSHKGFHYK, from the internal region of the protein sequence according to NP_848018.1; NP_777568.1. Corresponding Immunizing Peptide: Catalog #MBS425952
other info2 :
Important Note: This antibody is expected to recognise both reported isoforms of human Ymer protein.
ncbi gi num :
41281911
ncbi acc num :
NP_848018.1
ncbi gb acc num :
NM_178335.2
ncbi mol weight :
56,340 Da
ncbi summary :
This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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