catalog number :
MBS420642
products full name :
Goat anti-c-Myb (aa281-294) Antibody
products short name :
c-Myb
products name syn :
c-myb; MYB; v-myb myeloblastosis viral oncogene homolog (avian); c-myb_CDS; efg; Avian myeloblastosis viral (v-myb) oncogene homolog; c-myb protein (140 AA); c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; v-myb avian myeloblastosis viral oncogene homolog; v-myb myeloblastosis viral oncogene homolog; Goat Anti-c-MYB; c-myb; MYB; v-myb myeloblastosis viral oncogene homolog (avian); c-myb_CDS; efg; Avian myeloblastosis viral (v-myb) oncogene homolog; c-myb protein (140 AA); c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; v-myb avian myeloblastosis viral oncogene homolog; v-myb myeloblastosis viral oncogene homolog
other names :
transcriptional activator Myb isoform 1; Transcriptional activator Myb; transcriptional activator Myb; c-myb8B_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; proto-oncogene c-Myb; c-myb protein (140 AA); v-myb avian myeloblastosis viral oncogene homolog; Proto-oncogene c-Myb
other gene names :
MYB; MYB; efg; Cmyb; c-myb; c-myb_CDS
uniprot entry name :
MYB_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
QRHYNDEDPEKEKR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Kidney shows nuclear staining in all cells. Recommended concentration, 2-4ug/ml. Western Blot: Approx 70kDa band observed in Human Colon lysates (calculated MW of 72.3kDa according to NP_005366.2). Recommended concentration: 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:1000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QRHYNDEDPEKEKR, from the internal region of the protein sequence according to NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1. Corresponding Immunizing Peptide: Catalog #MBS428220
other info2 :
Important Note: This antibody is expected to recognize isoforms 1-7 only (Numbering from NCBI RefSeq). (NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1)
ncbi acc num :
NP_001123645.1
ncbi gb acc num :
NM_001130173.1
ncbi mol weight :
37,507 Da
ncbi pathways :
C-MYB Transcription Factor Network Pathway 138073!!Factors Involved In Megakaryocyte Development And Platelet Production Pathway 187196!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Hemostasis Pathway 106028!!IL2 Signaling Events Mediated By PI3K Pathway 137938!!IL4-mediated Signaling Events Pathway 137933!!Neural Crest Differentiation Pathway 672460!!Notch-mediated HES/HEY Network Pathway 169347!!PI3K-Akt Signaling Pathway 692234
ncbi summary :
This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]