catalog number :
MBS420641
products full name :
Goat anti-Kinesin 1/UKHC Antibody
products short name :
Kinesin 1/UKHC
products name syn :
KIF5B; UKHC; kinesin 1 (110-120kD); kinesin family member 5B; KNS; KINH; KNS1; U-KHC; kinesin heavy chain; KIF5B antibody; UKHC antibody; kinesin 1 (110-120kD) antibody; kinesin family member 5B antibody; KNS antibody; KINH antibody; KNS1 antibody; U-KHC antibody; kinesin heavy chain antibody; Kinesin 1; Kinesin 1 / UKHC
other names :
kinesin-1 heavy chain; Kinesin-1 heavy chain; kinesin-1 heavy chain; kinesin family member 5B; Conventional kinesin heavy chain; Ubiquitous kinesin heavy chain; UKHC
products gene name :
KIF5B
products gene name syn :
UKHC
other gene names :
KIF5B; KIF5B; KNS; KINH; KNS1; UKHC; HEL-S-61; KNS; KNS1; UKHC
uniprot entry name :
KINH_HUMAN
reactivity :
Tested: Human, Dog; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Immunohistochemistry: In paraffin embedded Human Kidney, shows perinuclear labelling of some glomerular cells and cytoplasmic staining of renal tubules. Recommended concentration, 1-2ug/ml. Please note this data was obtained with a previous batch (different goat). Western Blot: Approx 110kDa band observed in lysates of the cell lines Jurkat and HeLa (calculated MW of 110kDa according to NP_004512.1). Recommended concentration: 0.5-1.5ug/ml.
other info1 :
Immunogen: Peptide with sequence C-QPVAVRGGGGKQV, from the C Terminus of the protein sequence according to NP_004512.1. Epitope: C Terminus
ncbi acc num :
NP_004512.1
ncbi gb acc num :
NM_004521.2
ncbi mol weight :
109,685 Da
ncbi pathways :
Adaptive Immune System Pathway (1269171); COPI-dependent Golgi-to-ER Retrograde Traffic Pathway (1383042); Dopaminergic Synapse Pathway (469199); Dopaminergic Synapse Pathway (469185); Endocytosis Pathway (102279); Endocytosis Pathway (102181); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (1269377); Golgi-to-ER Retrograde Transport Pathway (1383041); Hemostasis Pathway (1269340); Immune System Pathway (1269170)
uniprot summary :
KIF5B: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Belongs to the kinesin-like protein family. Kinesin subfamily. Protein type: Motor; Microtubule-binding. Chromosomal Location of Human Ortholog: 10p11.22. Cellular Component: ciliary rootlet; cytoplasm; endocytic vesicle; kinesin complex; membrane; microtubule; microtubule organizing center; neuron projection; perinuclear region of cytoplasm; vesicle. Molecular Function: ATP binding; microtubule binding; microtubule motor activity; plus-end-directed microtubule motor activity; protein binding. Biological Process: axon guidance; cytoplasm organization and biogenesis; cytoskeleton-dependent intracellular transport; metabolic process; microtubule-based movement; positive regulation of potassium ion transport; positive regulation of synaptic transmission, GABAergic; regulation of membrane potential; vesicle transport along microtubule