product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Sall4 (mouse) Antibody
catalog :
MBS420629
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420629
products type :
Antibody
products full name :
Goat anti-Sall4 (mouse) Antibody
products short name :
Sall4
products name syn :
SALL4; sal-like 4 (Drosophila); AA407717; AL022809; AW536104; C330011P20Rik; C78083; C78563; Tex20; sal-like 4; SALL4 antibody; sal-like 4 (Drosophila) antibody; AA407717 antibody; AL022809 antibody; AW536104 antibody; C330011P20Rik antibody; C78083 antibody; C78563 antibody; Tex20 antibody; sal-like 4 antibody; Sall4 (mouse)
other names :
sal-like protein 4 isoform a; Sal-like protein 4; sal-like protein 4; sal-like 4 (Drosophila); Zinc finger protein SALL4
products gene name :
Sall4
other gene names :
Sall4; Sall4; Tex20; C78083; C78563; AA407717; AL022809; AW536104; 5730441M18Rik; C330011P20Rik
uniprot entry name :
SALL4_MOUSE
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Rat; Expected from sequence similarity: Mouse
sequence length :
1067
sequence :
DQSKKGKGKPQN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000.
other info1 :
Immunogen: Peptide with sequence C-DQSKKGKGKPQN, from the internal region of the protein sequence according to NP_780512.2; NP_958797.2; NP_958798.2. Epitope: Internal region
other info2 :
Note: This antibody is expected to recognize isoform a (NP_780512.2) and isoform b (NP_958797.2).
ncbi gi num :
117553631
ncbi acc num :
NP_780512.2
ncbi gb acc num :
NM_175303.4
ncbi mol weight :
29,725 Da
ncbi pathways :
PluriNetWork Pathway (198307)
ncbi summary :
This gene belongs to the spalt family of zinc finger transcription factors. In mouse, functions for this gene have been described in many embryonic developmental processes, including brain, heart, and limb development. In addition, this gene is an important pluripotency factor that is required for stem cell maintenance. Homozygous mutant mice display embryonic lethality, while conditional knock-out in embryonic germ cells results in failure to establish a robust stem cell population. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
uniprot summary :
SALL4: a transcription factor and oncofetal protein expressed embryonically and in the testis. Plays a key role in maintenance and self-renewal of embryonic stem cells. Interacts with NANOG and OCT4. Ectopically expressed in acute B-cell lymphoblastic leukemia (B-ALL) and myeloid leukemia (AML), playing a role in the survival of B-ALL cells and in myeloid leukemogenesis. Aberrantly expressed in multiple carcinomas including human gastric carcinoma and hepatocellular carcinoma. Maintains the stem cell qualities of EpCAM-positive hepatocellular carcinoma cells. Expressed in primary human endometrial cancer samples but not normal or hyperplastic endometrial cells. Its expression in carcinomas positively correlates with metastatic potential and poor patient survival. Specifically binds the c-Myc promoter region in endometrial cancer cells, apparently increasing c-Myc expression. Belongs to the sal C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cancer Testis Antigen (CTA); C2H2-type zinc finger protein; DNA-binding. Cellular Component: cytoplasm; heterochromatin; intracellular membrane-bound organelle; nucleoplasm; nucleus; protein complex; transcription factor complex. Molecular Function: DNA binding; metal ion binding; nucleic acid binding; protein binding; sequence-specific DNA binding; transcription factor activity. Biological Process: embryonic limb morphogenesis; heart development; in utero embryonic development; inner cell mass cell proliferation; negative regulation of transcription from RNA polymerase II promoter; neural tube closure; neural tube development; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; signal transduction; stem cell maintenance; tissue development; transcription, DNA-dependent
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!