catalog number :
MBS420622
products full name :
Goat anti-BCOR / BCL6 co-repressor Antibody
products short name :
BCOR/BCL6 co-repressor
products name syn :
BCOR; BCL-6 interacting corepressor; FLJ20285; KIAA1575; BCL6 co-repressor; ANOP2; FLJ38041; MAA2; MGC131961; MGC71031; 5830466J11Rik; 8430401K06Rik; MCOPS2; BCOR; BCL-6 interacting corepressor; FLJ20285; KIAA1575; BCL6 co-repressor; ANOP2; FLJ38041; MAA2; MGC131961; MGC71031; 5830466J11Rik; 8430401K06Rik; MCOPS2
other names :
BCL-6 corepressor isoform a; BCL-6 corepressor; BCL-6 corepressor; BCL-6 interacting corepressor; BCL6 corepressor
products gene name :
BCOR
other gene names :
BCOR; BCOR; MAA2; ANOP2; MCOPS2; KIAA1575; BCoR
uniprot entry name :
BCOR_HUMAN
reactivity :
Human, Mouse, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Chromatin Immunoprecipitation (ChIP), Western Blot (WB)
app notes :
Western Blot: Preliminary experiments gave no signal but low background in human testis and 293 cell lysates at up to 1ug/ml. Peptide ELISA: antibody detection limit dilution 1:2000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence LSATPLYGNVHSW-C, from the N Terminus of the protein sequence according to NP_060215.4; NP_001116855.1; NP_001116856.1; NP_001116857.1. Corresponding Immunizing Peptide: Catalog #MBS425696
other info2 :
Important Note: This antibody is expected to recognise all reported isoforms. Variants (NP_060215.4; NP_001116855.1) encode the same isoform.
ncbi acc num :
NP_060215.4
ncbi gb acc num :
NM_017745.5
ncbi mol weight :
186,235 Da
ncbi pathways :
Signaling Events Mediated By HDAC Class II Pathway 138062
ncbi summary :
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]