antibody

Goat anti-ERK2 / MAPK1 Antibody

MBS420619

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, mouse, rat, dog, cow

western blot, enzyme immunoassay

Antibody

Goat anti-ERK2 / MAPK1 Antibody

ERK2/MAPK1

MAPK1; ERK2; ERK; p38; p40; p41; ERT1; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; mitogen-activated protein kinase 1; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; MAPK1; ERK2; ERK; p38; p40; p41; ERT1; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; mitogen-activated protein kinase 1; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; extracellular signal-regulated kinase-2

mitogen-activated protein kinase 1; Mitogen-activated protein kinase 1; mitogen-activated protein kinase 1; MAPK 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; protein tyrosine kinase ERK2; mitogen-activated protein kinase 2; extracellular signal-regulated kinase 2; mitogen-activated protein kinase 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2

MAPK1

MAPK1; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; ERK2; PRKM1; PRKM2; MAP kinase 1; MAPK 1; ERK-2; p42-MAPK; MAP kinase 2; MAPK 2

MK01_HUMAN

Polyclonal

Goat

Human, Mouse, Rat, Dog, Cow

360

CAAGPEMVRGQVF

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Approx 38kDa band observed in human cervix epitheloid carcinoma HeLa and and human hepatoblastoma HepG2 lysates (calculated MW of 41.4kDa according to NP_002736 and NP_620407). Recommended concentration: 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.

Epitope: Internal Region. Immunogen: Peptide with sequence CAAGPEMVRGQVF, from the internal region of the protein sequence according to NP_002736.3; NP_620407.1. Corresponding Immunizing Peptide: Catalog #MBS425003

Important Note: This antibody is expected to recognise an epitope corresponding to aa 9-19 of both reported protein isoforms of human ERK2 / MAPK1 protein.

66932916

NP_002736.3

NM_002745.4

36,432 Da

AGE/RAGE Pathway 698754!!ALK1 Signaling Events Pathway 137968!!ARMS-mediated Activation Pathway 106466!!ATF-2 Transcription Factor Network Pathway 138006!!Activated TLR4 Signalling Pathway 106400!!Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway 161033!!Activation Of The AP-1 Family Of Transcription Factors Pathway 160139!!Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Adherens Junction Pathway 83070

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

0.1 mg

290 USD