catalog number :
MBS420608
products full name :
Goat anti-Tafazzin Antibody
products short name :
Tafazzin
products name syn :
TAZ; tafazzin (cardiomyopathy; dilated 3A (X-linked) endocardial fibroelastosis 2 Barth syndrome); HGNC:11577; BTHS; CMD3A; EFE; EFE2; G4.5; XAP-2; OTTHUMP00000061673; cardiomyopathy; dilated 3A (X-linked); tafazzin; XX-FW83563B9.3; FLJ27390; Taz1; LVNCX; TAZ; tafazzin (cardiomyopathy, dilated 3A (X-linked) endocardial fibroelastosis 2 Barth syndrome); HGNC:11577; BTHS; CMD3A; EFE; EFE2; G4.5; XAP-2; OTTHUMP00000061673; cardiomyopathy, dilated 3A (X-linked); tafazzin; XX-FW83563B9.3; FLJ27390; Taz1; LVNCX
other names :
tafazzin isoform 1; Tafazzin; tafazzin; protein G4.5; tafazzin; Protein G4.5
other gene names :
TAZ; TAZ; EFE; BTHS; EFE2; G4.5; Taz1; CMD3A; LVNCX; EFE2; G4.5
uniprot entry name :
TAZ_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 28kDa band observed in Human Heart lysates (calculated MW of 33.5kDa according to NP_000107.1, 30.2kDa according to NP_851828.1, 31.7kDa according to NP_851829.1 and 28.5 according to NP_851830.1). Recommended concentration: 0.3-1.0 ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-HLKTQAEQLHNH, from the C Terminus of the protein sequence according to NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1. Corresponding Immunizing Peptide: Catalog #MBS426051
other info2 :
Important Note: This antibody is expected to recognise isoforms 1to 4 (NP_000107.1; NP_851828.1; NP_851829.1; NP_851830.1, respectively).
ncbi acc num :
NP_000107.1
ncbi gb acc num :
NM_000116.3
ncbi mol weight :
25,836 Da
ncbi pathways :
Acyl Chain Remodeling Of CL Pathway 645330!!Glycerophospholipid Biosynthesis Pathway 645313!!Glycerophospholipid Metabolism Pathway 82989!!Glycerophospholipid Metabolism Pathway 364!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Metabolism Of Proteins Pathway 106230!!Mitochondrial Protein Import Pathway 576261!!Phospholipid Metabolism Pathway 645312
ncbi summary :
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq, Jul 2008]