catalog number :
MBS420592
products full name :
Goat anti-IGFBP7 (aa194-207) Antibody
products short name :
IGFBP7
products name syn :
IGFBP7; insulin-like growth factor binding protein 7; FSTL2; IGFBP-7; IGFBP-7v; MAC25; PSF; Goat Anti-IGFBP7 (aa145-159); IGFBP7; insulin-like growth factor binding protein 7; FSTL2; IGFBP-7; IGFBP-7v; MAC25; PSF
other names :
insulin-like growth factor-binding protein 7 isoform 1; Insulin-like growth factor-binding protein 7; insulin-like growth factor-binding protein 7; IGFBP-rP1; angiomodulin; IGF-binding protein 7; PGI2-stimulating factor; tumor-derived adhesion factor; prostacyclin-stimulating factor; insulin-like growth factor binding protein 7; IGFBP-rP1; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor; TAF
products gene name :
IGFBP7
other gene names :
IGFBP7; IGFBP7; AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; MAC25; PSF; IBP-7; IGF-binding protein 7; IGFBP-7; TAF
uniprot entry name :
IBP7_HUMAN
sequence :
NKVKRGHYGVQRTE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments gave an approx 50kDa band in Human Kidney, Spleen, Ovary, Prostate and Testis lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 29.1kDa according to NP_001544.1. The 50kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-NKVKRGHYGVQRTE, from the internal region of the protein sequence according to NP_001544.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428640
ncbi acc num :
NP_001544.1
ncbi gb acc num :
NM_001553.2
ncbi mol weight :
28,860 Da
ncbi pathways :
Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Senescence And Autophagy Pathway 198780!!Senescence-Associated Secretory Phenotype (SASP) Pathway 905996
ncbi summary :
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]