antibody

Goat anti-FBXL10 / PCCX2 Antibody

MBS420571

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, mouse, rat, dog

western blot, enzyme immunoassay

Antibody

Goat anti-FBXL10 / PCCX2 Antibody

FBXL10/PCCX2

KDM2B; lysine (K)-specific demethylase 2B; FBL10; FBXL10; F-box and leucine-rich repeat protein 10; CXXC2; Fbl10; JHDM1B; PCCX2; JEMMA (Jumonji domain; EMSY-interactor; methyltransferase motif) protein; protein containing CXXC domain 2; jumonji C domain-containing histone demethylase 1B; KDM2B; lysine (K)-specific demethylase 2B; FBL10; FBXL10; F-box and leucine-rich repeat protein 10; CXXC2; Fbl10; JHDM1B; PCCX2; JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein; protein containing CXXC domain 2; jumonji C domain-containing histone demethylase 1B

lysine-specific demethylase 2B isoform a; Lysine-specific demethylase 2B; lysine-specific demethylase 2B; F-box protein FBL10; F-box/LRR-repeat protein 10; CXXC-type zinc finger protein 2; protein-containing CXXC domain 2; [Histone-H3]-lysine-36 demethylase 1B; F-box and leucine-rich repeat protein 10; jumonji C domain-containing histone demethylase 1B; jmjC domain-containing histone demethylation protein 1B; JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein; lysine (K)-specific demethylase 2B; CXXC-type zinc finger protein 2; F-box and leucine-rich repeat protein 10; F-box protein FBL10; F-box/LRR-repeat protein 10; JmjC domain-containing histone demethylation protein 1B; Jumonji domain-containing EMSY-interactor methyltransferase motif protein; Protein JEMMA; Protein-containing CXXC domain 2; [Histone-H3]-lysine-36 demethylase 1B

KDM2B

KDM2B; KDM2B; CXXC2; Fbl10; PCCX2; FBXL10; JHDM1B; CXXC2; FBL10; FBXL10; JHDM1B; PCCX2; Protein JEMMA

KDM2B_HUMAN

Polyclonal

Goat

Human, Mouse, Rat, Dog

1336

FGQVEEKLLQKLS

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Customer's experiments gave bands at approx 170+90kDa in lysates of celll line HeLa (calculated MW of 153kDa according to NP_115979.3). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: C Terminus. Immunogen: Peptide with sequence C-FGQVEEKLLQKLS, from the C Terminus of the protein sequence according to NP_115979.3. Corresponding Immunizing Peptide: Catalog #MBS425826

Important Note: This antibody is expected to recognize isoform a (NP_115979.3) only.

54112382

NP_115979.3

NM_032590.4

144,769 Da

Chromatin Modifying Enzymes Pathway 941403!!Chromatin Organization Pathway 941402!!HDMs Demethylate Histones Pathway 1016171

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD