catalog number :
MBS420559
products full name :
Goat anti-ARP1 homolog A Antibody
products short name :
ARP1 homolog A
products name syn :
ACTR1A; ARP1; ARP1 actin-related protein 1 homolog A; centractin alpha (yeast); actin-RPV; centractin alpha; ARP1; yeast homolog A; centrosome-associated actin homolog; ARP1 (actin-related protein 1; yeast) homolog A (centractin alpha); CTRN1; FLJ52695; FLJ52800; FLJ55002; ARP1 actin-related protein 1 homolog A; centractin alpha; ARP1; ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); actin-RPV; centractin alpha; ARP1, yeast homolog A; centrosome-associated actin homolog; ARP1 (actin-related protein 1, yeast) homolog A (centractin alpha); CTRN1; FLJ52695; FLJ52800; FLJ55002; ARP1 actin-related protein 1 homolog A, centractin alpha
other names :
alpha-centractin; Alpha-centractin; alpha-centractin; actin-RPV; centrosome-associated actin homolog; ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); ARP1; Actin-RPV; Centrosome-associated actin homolog
products gene name :
ACTR1A
other gene names :
ACTR1A; ACTR1A; ARP1; CTRN1; CTRN1; Centractin
uniprot entry name :
ACTZ_HUMAN
reactivity :
Human, Mouse, Dog, Pig
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx. 45kDa band observed in Human Kidney lysates (calculated MW of 42.6kDa according to NP_005727.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:1000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-YEEDGARSIHRKT, from the C Terminus of the protein sequence according to NP_005727.1. Corresponding Immunizing Peptide: Catalog #MBS426274
other info2 :
Important Note: This epitope was selected to minimise the chance of cross-reactivity with ACTR1B (YEEDGSRAIHRKT).
ncbi acc num :
NP_005727.1
ncbi gb acc num :
NM_005736.3
ncbi mol weight :
42,614 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Centrosome Maturation Pathway 105807!!G2/M Transition Pathway 105801!!Immune System Pathway 106386!!Loss Of Nlp From Mitotic Centrosomes Pathway 105811!!Loss Of Proteins Required For Interphase Microtubule Organization From The Centrosome Pathway 105810!!MHC Class II Antigen Presentation Pathway 645290!!Mitotic G2-G2/M Phases Pathway 160942
ncbi summary :
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq, Jul 2008]