antibody

Goat anti-BAIAP2 (isoform 3) Antibody

MBS420537

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, dog, cow

western blot, enzyme immunoassay

Antibody

Goat anti-BAIAP2 (isoform 3) Antibody

BAIAP2

BAIAP2; BAP2; IRSP53; BAI1-associated protein 2; FLAF3; brain-specific angiogenesis inhibitor 1-associated protein 2; fas ligand-associated factor 3; insulin receptor substrate p53; insulin receptor substrate p53/p58; Goat Anti-BAIAP2 (isoform 1); BAIAP2; BAP2; IRSP53; BAI1-associated protein 2; FLAF3; brain-specific angiogenesis inhibitor 1-associated protein 2; fas ligand-associated factor 3; insulin receptor substrate p53; insulin receptor substrate p53/p58

brain-specific angiogenesis inhibitor 1-associated protein 2 isoform 3; Brain-specific angiogenesis inhibitor 1-associated protein 2; brain-specific angiogenesis inhibitor 1-associated protein 2; IRS-58; IRSp53/58; fas ligand-associated factor 3; insulin receptor substrate p53/p58; insulin receptor substrate protein of 53 kDa; BAI1-associated protein 2; Fas ligand-associated factor 3; FLAF3; Insulin receptor substrate p53/p58; IRS-58; IRSp53/58; Insulin receptor substrate protein of 53 kDa; IRSp53; Insulin receptor substrate p53

BAIAP2

BAIAP2; BAIAP2; BAP2; FLAF3; IRSP53; BAI-associated protein 2; BAI1-associated protein 2; Protein BAP2; FLAF3; IRS-58; IRSp53/58; IRSp53; Insulin receptor substrate p53

BAIP2_HUMAN

Polyclonal

Goat

Human, Dog, Cow

520

SMSSADVEVARF

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: In transfected HEK293 transiently expressing full-length Human BAIAP2 (myc and DYKDDDDK tagged), a band of approx. 60kDa was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-DYKDDDDK tag antibody. Recommended concentration, 1-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.

Epitope: C Terminus. Immunogen: Peptide with sequence C-SMSSADVEVARF, from the C Terminus of the protein sequence according to NP_006331.1. Corresponding Immunizing Peptide: Catalog #MBS428335

Important Note: This antibody will recognise only one of three reported isoforms (NP_006331.1).

5453565

NP_006331.1

NM_006340.2

57,430 Da

Adherens Junction Pathway 83070!!Adherens Junction Pathway 481!!CDC42 Signaling Events Pathway 137994!!ErbB1 Downstream Signaling Pathway 138057!!Fcgamma Receptor (FCGR) Dependent Phagocytosis Pathway 771577!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!RAC1 Signaling Pathway 169355!!Regulation Of Actin Cytoskeleton Pathway 198874!!Regulation Of Actin Cytoskeleton Pathway 83089

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Jan 2009]

0.1 mg

290 USD