catalog number :
MBS420505
products full name :
Goat anti-IBP / DEF6 Antibody
products short name :
IBP/DEF6
products name syn :
DEF6; IBP; differentially expressed in FDCP 6 homolog; RP3-329A5.5; SLAT; IRF4-binding protein; OTTHUMP00000016251; differentially expressed in FDCP 6 homolog (mouse); SWAP70L; SWAP-70-like adaptor protein of T cells; DEF6; IBP; differentially expressed in FDCP 6 homolog; RP3-329A5.5; SLAT; IRF4-binding protein; OTTHUMP00000016251; differentially expressed in FDCP 6 homolog (mouse); SWAP70L; SWAP-70-like adaptor protein of T cells
other names :
differentially expressed in FDCP 6 homolog; Differentially expressed in FDCP 6 homolog; differentially expressed in FDCP 6 homolog; DEF-6; IRF4-binding protein; SWAP-70-like adaptor protein of T cells; differentially expressed in FDCP 6 homolog (mouse); IRF4-binding protein
products gene name :
DEF6
other gene names :
DEF6; DEF6; IBP; SLAT; SWAP70L; IBP; DEF-6
uniprot entry name :
DEFI6_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx. 70kDa band observed in Human Thymus lysates (calculated MW of 73.9kDa according to NP_071330.3). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:2000.
other info1 :
Epitope: N Terminus. Immunogen: Peptide with sequence ALRKELLKSIWYA-C, from the N Terminus of the protein sequence according to NP_071330.3.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425424
ncbi acc num :
NP_071330.3
ncbi gb acc num :
NM_022047.3
ncbi mol weight :
73,910 Da
ncbi pathways :
Regulation Of RAC1 Activity Pathway 169346!!Regulation Of RhoA Activity Pathway 138070
ncbi summary :
DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM, Mar 2008]