catalog number :
MBS420502
products full name :
Goat anti-ICSBP1 / IRF8 Antibody
products short name :
ICSBP1/IRF8
products name syn :
IRF8; ICSBP1; interferon consensus sequence binding protein 1; IRF-8; H-ICSBP; interferon regulatory factor 8; IRF8; ICSBP1; interferon consensus sequence binding protein 1; IRF-8; H-ICSBP; interferon regulatory factor 8
other names :
interferon regulatory factor 8; Interferon regulatory factor 8; interferon regulatory factor 8; interferon consensus sequence binding protein 1; interferon regulatory factor 8; Interferon consensus sequence-binding protein; H-ICSBP; ICSBP
products gene name :
IRF8
other gene names :
IRF8; IRF8; ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP; ICSBP1; IRF-8; H-ICSBP; ICSBP
uniprot entry name :
IRF8_HUMAN
reactivity :
Human, Mouse, Rat, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 45-50kDa band seen in K562 lysate (Predicted MW of 47kDa according to NP_002154). Recommended for use at 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-QRSFFRENQQITV, from the C Terminus of the protein sequence according to NP_002154.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425759
ncbi acc num :
NP_002154.1
ncbi gb acc num :
NM_002163.2
ncbi mol weight :
48,356 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway 366171!!Immune System Pathway 106386!!Interferon Signaling Pathway 187103!!Interferon Alpha/beta Signaling Pathway 187104!!Interferon Gamma Signaling Pathway 187106!!Pertussis Pathway 218111!!Pertussis Pathway 218099!!Type II Interferon Signaling (IFNG) Pathway 198918!!Validated Targets Of C-MYC Transcriptional Repression Pathway 169353
ncbi summary :
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq, Jul 2008]