catalog number :
MBS420494
products full name :
Goat anti-Neuroligin 3 Antibody
products short name :
Neuroligin 3
products name syn :
neuroligin 3; KIAA1480; ASPGX1; AUTSX1; HNL3; NLGN3; neuroligin 3; KIAA1480; ASPGX1; AUTSX1; HNL3; NLGN3
other names :
neuroligin-3 isoform 2; Neuroligin-3; neuroligin-3; gliotactin homolog; neuroligin 3; Gliotactin homolog
products gene name :
NLGN3
other gene names :
NLGN3; NLGN3; HNL3; KIAA1480; NL3
uniprot entry name :
NLGN3_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
RKDKRRQEPLRQPS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx. 85-90kDa band observed in Human Brain (Amygdala) lysates (calculated MW of 91.6kDa according to NP_061850.2). In transfected HEK293 transiently expressing Neuregulin3 a band of approx. 98kDa is observed. This band is not observed in the non-transfected HEK293. Recommended concentration: 0.05-0.2ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-RKDKRRQEPLRQPS, from the internal region of the protein sequence according to NP_061850.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426686
ncbi acc num :
NP_061850.2
ncbi gb acc num :
NM_018977.3
ncbi mol weight :
89,538 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480
ncbi summary :
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Oct 2009]