This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-GRHR / LRHR Antibody
catalog :
MBS420493
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, dog
application :
western blot, enzyme immunoassay
product information
catalog number :
MBS420493
products type :
Antibody
products full name :
Goat anti-GRHR / LRHR Antibody
products short name :
GRHR/LRHR
products name syn :
GNRHR; LRHR; gonadotropin-releasing hormone receptor; GNRHR1; GRHR; LHRHR; gonadotropin-releasing hormone (type 1) receptor 1; leutinizing hormone releasing horomone receptor; leutinizing-releasing hormone receptor; luliberin receptor; type I GnRH receptor; GNRHR; LRHR; gonadotropin-releasing hormone receptor; GNRHR1; GRHR; LHRHR; gonadotropin-releasing hormone (type 1) receptor 1; leutinizing hormone releasing horomone receptor; leutinizing-releasing hormone receptor; luliberin receptor; type I GnRH receptor
other names :
gonadotropin-releasing hormone receptor isoform 1; Gonadotropin-releasing hormone receptor; gonadotropin-releasing hormone receptor; gnRH-R; gnRH receptor; luliberin receptor; type I GnRH receptor; leutinizing-releasing hormone receptor; leutinizing hormone releasing horomone receptor; gonadotropin-releasing hormone (type 1) receptor 1; gonadotropin-releasing hormone receptor
products gene name :
GNRHR
other gene names :
GNRHR; GNRHR; HH7; GRHR; LRHR; LHRHR; GNRHR1; GRHR; GnRH receptor; GnRH-R
uniprot entry name :
GNRHR_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Dog
sequence length :
328
sequence :
QKWTQKKEKGK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 60kDa band observed in Human lysates of Peripheral Blood Mononucleocytes (calculated MW of 37.7kDa according to NP_000397.1). The observed molecular weight corresponds to earlier findings with products from other commercial sources. Recommended concentration: 0.5-1.5ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QKWTQKKEKGK, from the internal region of the protein sequence according to NP_000397.1; NP_001012781.1. Corresponding Immunizing Peptide: Catalog #MBS426795
other info2 :
Important Note: This antibody is expected to recognise both reported isoforms (NP_000397.1; NP_001012781.1).
ncbi gi num :
4504059
ncbi acc num :
NP_000397.1
ncbi gb acc num :
NM_000406.2
ncbi mol weight :
27,727 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!GPCRs, Other Pathway 198765!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!GnRH Signaling Pathway 83091!!GnRH Signaling Pathway 502!!Hormone Ligand-binding Receptors Pathway 106369!!Neuroactive Ligand-receptor Interaction Pathway 83053
ncbi summary :
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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