product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Renalase (aa 134 to 147) Antibody
catalog :
MBS420455
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS420455
products type :
Antibody
products full name :
Goat anti-Renalase (aa 134 to 147) Antibody
products short name :
Renalase
products name syn :
Goat Anti-Renalase (aa 224 to 233) Antibody; renalase; C10orf59; chromosome 10 open reading frame 59; FLJ11218; renalase antibody; C10orf59 antibody; chromosome 10 open reading frame 59 antibody; FLJ11218 antibody; Renalase; Renalase (aa 134 to 147)
other names :
renalase isoform 1; Renalase; renalase; renalase, FAD-dependent amine oxidase; Monoamine oxidase-C; MAO-C
products gene name :
C10orf59
other gene names :
RNLS; RNLS; C10orf59; RENALASE; C10orf59; MAO-C
uniprot entry name :
RNLS_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Mouse, Rat; Expected from sequence similarity: Human, Mouse, Rat
sequence length :
342
sequence :
QINLRDDKWEVSKQ
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 37kDa band observed in Mouse Kidney and Rat Kidney lysates (calculated MW of 37.8kDa according to Human NP_001026879.1 and 35. 0kDa according to Rat NP_001014189.1). Recommended concentration: 0.5-1.5ug/ml.
other info1 :
Immunogen: Peptide with sequence C-QINLRDDKWEVSKQ, from the Internal region of the protein sequence according to NP_001026879.1; NP_060833.1. Epitope: Internal region
other info2 :
Note: This antibody is expected to recognize both reported isoforms (NP_001026879.1 and NP_060833.1).
ncbi gi num :
72534708
ncbi acc num :
NP_001026879.1
ncbi gb acc num :
NM_001031709.1
ncbi mol weight :
34,949 Da
ncbi summary :
Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005 [PubMed 15841207]).[supplied by OMIM, Mar 2008]
uniprot summary :
RENALASE: Probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. Degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. According to PubMed:17385068, is unlikely that renalase has physiologically relevant catecholamine-oxidizing activity. Belongs to the renalase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Oxidoreductase; Secreted, signal peptide; Secreted; EC 1.6.3.5. Chromosomal Location of Human Ortholog: 10q23.31. Cellular Component: extracellular space. Molecular Function: oxidoreductase activity
size1 :
0.1 mg
price1 :
300 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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