catalog number :
MBS420451
products full name :
Goat anti-HSPA8 (Isoform 1) Antibody
products short name :
HSPA8
products name syn :
HSPA8; heat shock 70kDa protein 8; HSC54; HSC70; HSC71; HSP71; HSP73; HSPA10; LAP; MGC131511; MGC29929; NIP71; LPS-associated protein 1; N-myristoyltransferase inhibitor protein 71; constitutive heat shock protein 70; heat shock 70kD protein 8; heat shock 70kd protein 10; heat shock cognate protein 54; heat shock cognate protein; 71-kDa; lipopolysaccharide-associated protein; uncharacterized bone marrow protein BM034; HSPA8; heat shock 70kDa protein 8; HSC54; HSC70; HSC71; HSP71; HSP73; HSPA10; LAP; MGC131511; MGC29929; NIP71; LPS-associated protein 1; N-myristoyltransferase inhibitor protein 71; constitutive heat shock protein 70; heat shock 70kD protein 8; heat shock 70kd protein 10; heat shock cognate protein 54; heat shock cognate protein; 71-kDa; lipopolysaccharide-associated protein; uncharacterized bone marrow protein BM034
other names :
heat shock cognate 71 kDa protein isoform 1; Heat shock cognate 71 kDa protein; heat shock cognate 71 kDa protein; LPS-associated protein 1; heat shock 70kd protein 10; epididymis luminal protein 33; heat shock cognate protein 54; constitutive heat shock protein 70; lipopolysaccharide-associated protein 1; N-myristoyltransferase inhibitor protein 71; epididymis secretory sperm binding protein Li 72p; heat shock 70kDa protein 8; Heat shock 70 kDa protein 8; Lipopolysaccharide-associated protein 1; LAP-1; LPS-associated protein 1
products gene name :
HSPA8
other gene names :
HSPA8; HSPA8; LAP1; HSC54; HSC70; HSC71; HSP71; HSP73; LAP-1; NIP71; HEL-33; HSPA10; HEL-S-72p; HSC70; HSP73; HSPA10; LAP-1; LPS-associated protein 1
uniprot entry name :
HSP7C_HUMAN
reactivity :
Human, Mouse, Rat, Dog
sequence :
EKLQGKINDEDKQK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 75kDa band observed in lysates of cell line A431 (calculated MW of 70.9kDa according to NP_006588.1). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-EKLQGKINDEDKQK, from the internal region of the protein sequence according to NP_006588.1. Corresponding Immunizing Peptide: Catalog #MBS425020
other info2 :
Important Note: This antibody is expected to recognise isoform 1 (NP_006588.1) only.
ncbi acc num :
NP_006588.1
ncbi gb acc num :
NM_006597.5
ncbi mol weight :
53,518 Da
ncbi pathways :
AUF1 (hnRNP D0) Destabilizes MRNA Pathway 187212!!Antigen Processing And Presentation Pathway 83074!!Antigen Processing And Presentation Pathway 485!!Attenuation Phase Pathway 980473!!Axon Guidance Pathway 105688!!C-MYB Transcription Factor Network Pathway 138073!!CHL1 Interactions Pathway 161007!!Cellular Response To Heat Stress Pathway 980470!!Cellular Responses To Stress Pathway 645258!!Clathrin Derived Vesicle Budding Pathway 119545
ncbi summary :
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]