catalog number :
MBS420450
products full name :
Goat anti-VPS35 / MEM3 Antibody
products short name :
VPS35/MEM3
products name syn :
VPS35; MEM3; FLJ10752; FLJ13588; FLJ20388; DKFZp434E1211; DKFZp434P1672; vacuolar protein sorting 35 (yeast); maternal-embryonic 3; vacuolar protein sorting 35 homolog (S. cerevisiae); vacuolar protein sorting 35; VPS35; MEM3; FLJ10752; FLJ13588; FLJ20388; DKFZp434E1211; DKFZp434P1672; vacuolar protein sorting 35 (yeast); maternal-embryonic 3; vacuolar protein sorting 35 homolog (S. cerevisiae); vacuolar protein sorting 35
other names :
vacuolar protein sorting-associated protein 35; Vacuolar protein sorting-associated protein 35; vacuolar protein sorting-associated protein 35; hVPS35; maternal-embryonic 3; vacuolar protein sorting 35 homolog (S. cerevisiae); Maternal-embryonic 3; Vesicle protein sorting 35
products gene name :
VPS35
other gene names :
VPS35; VPS35; MEM3; PARK17; MEM3; hVPS35
uniprot entry name :
VPS35_HUMAN
reactivity :
Human, Mouse, Rat, Cow
sequence :
SPESEGPIYEGLIL
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-SPESEGPIYEGLIL, from the C Terminus of the protein sequence according to NP_060676.2. Corresponding Immunizing Peptide: Catalog #MBS426803
other info2 :
Important Note: Note there is a hypothetical protein called similar to vacuolar protein sorting 35 (XP_040192.1), which is virtually identical.
ncbi acc num :
NP_060676.2
ncbi gb acc num :
NM_018206.4
ncbi mol weight :
91,707 Da
ncbi pathways :
Disease Pathway 530764!!Signal Transduction Pathway 477114!!Signaling By WNT In Cancer Pathway 1016191!!Signaling By Wnt Pathway 106510!!WNT Ligand Biogenesis And Trafficking Pathway 833832!!WNT Ligand Secretion Is Abrogated By The PORCN Inhibitor LGK974 Pathway 1016211
ncbi summary :
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]