catalog number :
MBS420430
products full name :
Goat anti-DSS1 / SHFM1 Antibody
products short name :
DSS1/SHFM1
products name syn :
SHFM1; split hand/foot malformation (ectrodactyly) type 1; DSS1; Deleted in split-hand/split-foot 1 region; ECD; SEM1; SHFD1; SHSF1; Shfdg1; candidate for split hand/foot malformation type 1; deleted in split-hand/foot 1; deleted in split-hand/split-foot 1; split hand/foot malformation type 1; SHFM1; split hand/foot malformation (ectrodactyly) type 1; DSS1; Deleted in split-hand/split-foot 1 region; ECD; SEM1; SHFD1; SHSF1; Shfdg1; candidate for split hand/foot malformation type 1; deleted in split-hand/foot 1; deleted in split-hand/split-foot 1; split hand/foot malformation type 1
other names :
26S proteasome complex subunit DSS1; 26S proteasome complex subunit DSS1; 26S proteasome complex subunit DSS1; split hand/foot deleted protein 1; deleted in split-hand/split-foot 1; deleted in split hand/split foot protein 1; split hand/foot malformation type 1 protein; split hand/foot malformation (ectrodactyly) type 1; Deleted in split hand/split foot protein 1; Split hand/foot deleted protein 1; Split hand/foot malformation type 1 protein
products gene name :
SHFM1
other gene names :
SHFM1; SHFM1; ECD; DSS1; SEM1; SHFD1; SHSF1; Shfdg1; DSS1; SHFDG1
uniprot entry name :
DSS1_HUMAN
reactivity :
Human, Mouse, Dog, Cow, Pig
sequence :
RAELEKHGYKMETS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunocytochemistry (ICC), Western Blot (WB)
app notes :
Western Blot: No signal obtained yet but a preliminary experiment showed low background in Human Liver extract at up to 1ug/ml. This used our standard western blotting protocol which we would not expect to detect proteins as small as the predicted size of approx. 8KDa according to NP_006295. Peptide ELISA: antibody detection limit dilution 1:32000. Immunocytochemistry: Anonymous customer found nuclear staining in HT1080.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-RAELEKHGYKMETS, from the C Terminus of the protein sequence according to NP_006295.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426965
ncbi acc num :
NP_006295.1
ncbi gb acc num :
NM_006304.1
ncbi mol weight :
8,278 Da
ncbi pathways :
Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115!!Homologous Recombination Pathway 83046!!Homologous Recombination Pathway 454!!Proteasome Pathway 83040!!Proteasome Pathway 445!!Proteasome, 19S Regulatory Particle (PA700) Pathway 413447!!Proteasome, 19S Regulatory Particle (PA700) Pathway 890593
ncbi summary :
The product of this gene has been localized within the split hand/split foot malformation locus SHFM1 at chromosome 7. It has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle. [provided by RefSeq, Jul 2008]