catalog number :
MBS420423
products full name :
Goat anti-GPX3 Antibody
products short name :
GPX3
products name syn :
GPX3; glutathione peroxidase 3 (plasma); GPx-P; GSHPx-3; GSHPx-P; extracellular glutathione peroxidase; plasma glutathione peroxidase 3; GPX3; glutathione peroxidase 3 (plasma); GPx-P; GSHPx-3; GSHPx-P; extracellular glutathione peroxidase; plasma glutathione peroxidase 3
other names :
glutathione peroxidase 3; Glutathione peroxidase 3; glutathione peroxidase 3; GPx-3; plasma glutathione peroxidase; extracellular glutathione peroxidase; glutathione peroxidase 3 (plasma); Extracellular glutathione peroxidase; Plasma glutathione peroxidase; GPx-P; GSHPx-P
products gene name :
GPX3
other gene names :
GPX3; GPX3; GPx-P; GSHPx-3; GSHPx-P; GPXP; GPx-3; GSHPx-3; GPx-P; GSHPx-P
uniprot entry name :
GPX3_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: Frozen sections of Porcin Kidney shows vesicular staining of the cytoplasm in PCT epithelial cells. Recommended concentration, 20ug/ml. Western Blot: Approx 26kDa band observed in Mouse Kidney and Liver lysates (calculated MW of 27.7kDa according to Mouse NP_001077398.1 [isoform1], 25.4kDa according to Mouse NP_032187.2 [isoform 2] and 25.5kDa according to Human NP_002075.2). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:1000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-NQFGKQEPGENSE, from the internal region of the protein sequence according to NP_002075.2. Corresponding Immunizing Peptide: Catalog #MBS425753
other info2 :
Important Note: This antibody may cross-react with epididymis-specific GPX5 and olfactory epithelium-speciific GPX6
ncbi acc num :
NP_002075.2
ncbi gb acc num :
NM_002084.3
ncbi mol weight :
25,552 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway 82991!!Arachidonic Acid Metabolism Pathway 366!!Cellular Responses To Stress Pathway 645258!!Detoxification Of Reactive Oxygen Species Pathway 941400!!Folate Metabolism Pathway 198833!!Glutathione Metabolism Pathway 82973!!Glutathione Metabolism Pathway 198824!!Glutathione Metabolism Pathway 343!!Oxidative Stress Pathway 198916!!Selenium Metabolism And Selenoproteins Pathway 198846
ncbi summary :
This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jul 2008]