product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-AKAP6 Antibody
catalog :
MBS420399
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420399
products type :
Antibody
products full name :
Goat anti-AKAP6 Antibody
products short name :
AKAP6
products name syn :
AKAP6; ADAP6; PRKA6; mAKAP; ADAP100; AKAP100; KIAA0311; A kinase (PRKA) anchor protein 6; A-kinase anchor protein 100; MGC165020; A-kinase anchor protein 6; protein kinase A anchoring protein 6; AKAP6 antibody; ADAP6 antibody; PRKA6 antibody; mAKAP antibody; ADAP100 antibody; AKAP100 antibody; KIAA0311 antibody; A kinase (PRKA) anchor protein 6 antibody; A-kinase anchor protein 100 antibody; MGC165020 antibody; A-kinase anchor protein 6 antibody; protein kinase A anchoring protein 6 antibody
other names :
A-kinase anchor protein 6; A-kinase anchor protein 6; A-kinase anchor protein 6; A-kinase anchoring protein 6; A-kinase anchor protein 100 kDa; AKAP 100; Protein kinase A-anchoring protein 6; PRKA6; mAKAP
products gene name :
AKAP6
other gene names :
AKAP6; AKAP6; ADAP6; PRKA6; mAKAP; ADAP100; AKAP100; AKAP100; KIAA0311; AKAP-6; AKAP 100; PRKA6
uniprot entry name :
AKAP6_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
sequence length :
2319
sequence :
LTMSVTLSPLRSQ
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: This antibody showed a 190kDa band in lysates of Mouse Heart and of Mouse Parotid (salivary) gland as described by Wu et al, Am J Physiol Cell Physiol.2010 May;298(5): C1151-8. PMID: 20164376.
other info1 :
Immunogen: Peptide with sequence LTMSVTLSPLRSQ-C, from the N Terminus of the protein sequence according to NP_004265.3. Epitope: N Terminus
products references :
Wu CY, DiJulio DH, Jacobson KL, McKnight GS, Watson EL.; The contribution of AKAP5 in amylase secretion from mouse parotid acini.; Am J Physiol Cell Physiol.2010 May;298(5): C1151-8.; Pubmed 20164376
ncbi gi num :
21493045
ncbi acc num :
NP_004265.3
ncbi gb acc num :
NM_004274.4
ncbi mol weight :
120,243 Da
ncbi pathways :
G Protein Signaling Pathways (198849)
ncbi summary :
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008]
uniprot summary :
AKAP6: Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes. Protein type: Adaptor/scaffold. Chromosomal Location of Human Ortholog: 14q12. Cellular Component: caveola; cytoplasm; nuclear envelope; nuclear membrane; perinuclear region of cytoplasm; sarcoplasmic reticulum; T-tubule. Molecular Function: adenylate cyclase binding; protein anchor; protein binding; protein complex scaffold; protein kinase A binding. Biological Process: cAMP-mediated signaling; negative regulation of cAMP biosynthetic process; positive regulation of cell growth; positive regulation of NFAT protein import into nucleus; positive regulation of protein phosphatase type 2B activity; positive regulation of release of sequestered calcium ion into cytosol; protein targeting; regulation of action potential
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!