catalog number :
MBS420396
products full name :
Goat anti-TERF1 / PIN2 Antibody
products short name :
TERF1/PIN2
products name syn :
TERF1; PIN2; TRF; TRF1; TRBF1; hTRF1-AS; telomeric repeat binding factor (NIMA-interacting) 1; Telomeric repeat binding factor 1; telomeric repeat binding protein 1; FLJ41416; t-TRF1; Goat Anti-TERF1 / TRF1; TERF1; PIN2; TRF; TRF1; TRBF1; hTRF1-AS; telomeric repeat binding factor (NIMA-interacting) 1; Telomeric repeat binding factor 1; telomeric repeat binding protein 1; FLJ41416; t-TRF1
other names :
telomeric repeat-binding factor 1 isoform 2; Telomeric repeat-binding factor 1; telomeric repeat-binding factor 1; NIMA-interacting protein 2; telomeric protein Pin2/TRF1; TTAGGG repeat-binding factor 1; telomeric repeat binding factor (NIMA-interacting) 1; NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; Telomeric protein Pin2/TRF1
products gene name :
TERF1
other gene names :
TERF1; TERF1; TRF; PIN2; TRF1; TRBF1; t-TRF1; hTRF1-AS; PIN2; TRBF1; TRF; TRF1
uniprot entry name :
TERF1_HUMAN
reactivity :
Human, Pig, Cow
sequence :
TMKKLKLISSDSED
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 60-65kDa and 45kDa bands seen in HeLa lysate. Recommended for use at 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-TMKKLKLISSDSED, from the C Terminus of the protein sequence according to NP_003209.2; NP_059523.2. Corresponding Immunizing Peptide: Catalog #MBS425463
other info2 :
Important Note: This antibody is expected to recognise isoform 1 (NP_059523.2) and isoform 2 (NP_003209.2).
ncbi acc num :
NP_003209.2
ncbi gb acc num :
NM_003218.3
ncbi mol weight :
48,239 Da
ncbi pathways :
Cell Cycle Pathway 530733!!Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Chromosome Maintenance Pathway 161048!!DNA Damage/Telomere Stress Induced Senescence Pathway 905994!!Meiosis Pathway 477133!!Meiotic Synapsis Pathway 477134!!Packaging Of Telomere Ends Pathway 106548!!Regulation Of Telomerase Pathway 137987!!Shelterin Complex Pathway 470348
ncbi summary :
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]