catalog number :
MBS420376
products full name :
Goat anti-FRA1 / FOSL1 Antibody
products short name :
FRA1/FOSL1
products name syn :
FOSL1; FRA1; FOS-like antigen 1; HGNC:13718; fra-1; FOS-like antigen-1; FOSL1; FRA1; FOS-like antigen 1; HGNC:13718; fra-1; FOS-like antigen-1
other names :
fos-related antigen 1 isoform 1; Fos-related antigen 1; fos-related antigen 1; FOS-like antigen-1; FOS-like antigen 1
products gene name :
FOSL1
other gene names :
FOSL1; FOSL1; FRA; FRA1; fra-1; FRA1; FRA-1
uniprot entry name :
FOSL1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 26-28kDa band observed in Human Bone Marrow, Breast and Placenta lysates (calculated MW of 29.4kDa according to NP_005429.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:1000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QREIEELQKQKER, from the internal region of the protein sequence according to NP_005429.1. Corresponding Immunizing Peptide: Catalog #MBS426299
other info2 :
Important Note: No cross-reactivity is expected with V-FOS.
ncbi acc num :
NP_005429.1
ncbi gb acc num :
NM_005438.4
ncbi mol weight :
17,560 Da
ncbi pathways :
Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Calcium Signaling In The CD4+ TCR Pathway 137941!!Corticotropin-releasing Hormone Pathway 920957!!DNA Damage Response (only ATM Dependent) Pathway 198827!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Osteoclast Differentiation Pathway 193147!!Osteoclast Differentiation Pathway 193096!!Validated Targets Of C-MYC Transcriptional Activation Pathway 169351
ncbi summary :
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]