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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-CHD7 Antibody
catalog :
MBS420342
quantity :
0.1 mg
price :
225 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
ELISA, enzyme immunoassay
more info or order :
product information
catalog number :
MBS420342
products type :
Antibody
products full name :
Goat anti-CHD7 Antibody
products short name :
CHD7
products name syn :
chromodomain helicase DNA binding protein 7; FLJ20357; FLJ20361; IS3; KIAA1416; Scoliosis, idiopathic 3; chromodomain helicase DNA binding protein 7 antibody; FLJ20357 antibody; FLJ20361 antibody; IS3 antibody; KIAA1416 antibody; Scoliosis; idiopathic 3 antibody
other names :
chromodomain-helicase-DNA-binding protein 7 isoform 1; Chromodomain-helicase-DNA-binding protein 7; chromodomain-helicase-DNA-binding protein 7; chromodomain helicase DNA binding protein 7; ATP-dependent helicase CHD7
products gene name :
CHD7
other gene names :
CHD7; CHD7; CRG; HH5; IS3; KAL5; KIAA1416; CHD-7
uniprot entry name :
CHD7_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Expected from sequence similarity: Human, Mouse, Rat
sequence length :
2997
sequence :
KDEIDEFANSPSE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Preliminary experiments gave bands at approx 250kDa and 48kDa in Rat Spinal Cord lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 336kDa according to Human NP_060250.2 and 175kDa according to predicted Rat NP_001101376.1. Both detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain the additional bands).
other info1 :
Immunogen: Peptide with sequence C-KDEIDEFANSPSE, from the internal region of the protein sequence according to NP_060250.2. Epitope: Internal region
ncbi gi num :
54112403
ncbi acc num :
NP_060250.2
ncbi gb acc num :
NM_017780.3
ncbi mol weight :
101,085 Da
ncbi pathways :
Noncanonical Wnt Signaling Pathway (169354)
ncbi summary :
This gene encodes a protein that contains several helicase family domains. Mutations in this gene have been found in some patients with the CHARGE syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
uniprot summary :
CHD-7: Probable transcription regulator. May interact with CTCF. Interacts with CHD8. Widely expressed in fetal and adult tissues. Belongs to the SNF2/RAD54 helicase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Helicase; DNA-binding; EC 3.6.4.12; Nucleolus. Chromosomal Location of Human Ortholog: 8q12.2. Cellular Component: nucleolus; nucleus. Molecular Function: ATP binding; chromatin binding; helicase activity; protein binding. Biological Process: adult heart development; adult walking behavior; artery morphogenesis; blood circulation; central nervous system development; chromatin modification; cognition; cranial nerve development; embryonic hindlimb morphogenesis; female genitalia development; genitalia development; heart morphogenesis; in utero embryonic development; inner ear morphogenesis; limb development; nose development; olfactory behavior; olfactory bulb development; olfactory nerve development; palate development; positive regulation of multicellular organism growth; regulation of growth hormone secretion; regulation of neurogenesis; regulation of transcription, DNA-dependent; retina development in camera-type eye; rRNA processing; semicircular canal morphogenesis; sensory perception of sound; skeletal development; T cell differentiation; transcription, DNA-dependent. Disease: Charge Syndrome; Hypogonadotropic Hypogonadism 5 With Or Without Anosmia; Tracheoesophageal Fistula With Or Without Esophageal Atresia
size1 :
0.1 mg
price1 :
225 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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