catalog number :
MBS420335
products full name :
Goat anti-MEFV Antibody
products short name :
MEFV
products name syn :
MEFV; Mediterranean fever; HGNC:6998; FMF; MEF; TRIM20; Mediterranean fever protein; pyrin; MGC126560; MGC126586; marenostrin; MEFV; Mediterranean fever; HGNC:6998; FMF; MEF; TRIM20; Mediterranean fever protein; pyrin; MGC126560; MGC126586; marenostrin
other names :
pyrin isoform 1; Pyrin; pyrin; marenostrin; Mediterranean fever; Marenostrin
products gene name :
MEFV
other gene names :
MEFV; MEFV; FMF; MEF; TRIM20; MEF
uniprot entry name :
MEFV_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 80kDa band observed in Human Peripheral Blood Leukocyte lysate. Recommended concentration: 1-3ug/ml during overnight incubation. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-EHLKKLRKSGEEQ, from the internal region of the protein sequence according to NP_000234.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS425478
ncbi acc num :
NP_000234.1
ncbi gb acc num :
NM_000243.2
ncbi mol weight :
50,837 Da
ncbi pathways :
Immune System Pathway 106386!!Inflammasomes Pathway 366166!!Innate Immune System Pathway 106387!!NOD Pathway 198792!!NOD-like Receptor Signaling Pathway 122191!!NOD-like Receptor Signaling Pathway 122131!!Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways 366164!!The NLRP3 Inflammasome Pathway 366167
ncbi summary :
This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. [provided by RefSeq, Jul 2008]